酰嘧磺隆(标准品)Amidosulfuron质量规格:分析标准品Ratmonocytechemotacticprotein1/monocytechemotacticandactivatingfactor,MCP-1/MCAFELISAKit大鼠单核细胞趋化蛋白1(MCP-1/CCL2/MCAF)ELISA试剂盒规格:96T/48T 莠灭净(标准品)Ametryn质量规格:分析标准品,98.8% DNA甲基转移酶-3B(DNMT-3B)活性酶连续循环比色法定量...
The present work investigated the action of IL-33 on the release of the chemokines CCL5 and CCL2 from human MCs, as well as the inhibitory effect of the flavonoid 3',4',5,7-tetramethoxyflavone (methoxyluteolin). Stimulation of cultured human MCs (LAD2) and primary MCs (hCBMCs) by IL...
RAW264.7 cells were seeded in the upper chamber and treated with TCA (100 µM), in the presence or absence of JTE-013 (10 µM) for 24 h, while the chemoattractant (CCL2, 100 ng/mL) was added to the lower compartments. The migrated cells on the lower surface of the chamber were...
NF-κB (核因子活化B细胞κ轻链增强子)是调控DNA转录的蛋白复合物,存在于几乎所有类型的动物细胞中,参与细胞对刺激物(如压力、细胞因子、自由基、紫外辐射、氧化低密度脂蛋白、细菌或病毒抗原等)产生应答。最近发现NF-κB与癌症、炎症、自身免疫疾病、感染性休克、病毒干扰和不合适的免疫发育相关。因此NF-κB可作为药...
[13] Khorooshi R,Babcock AA,Owens T.NF-kappaB-driven STAT2and CCL2expression in astrocytes in response to brain injury[J].J Immunol,2008,181(10):7 284-7 291. [14] Anderson KJ,Scheff SW,Miller KM,et al.The phosphorylated axonal form of the neurofilament subunit NF-H(pNF-H)as a bl...
It was found that 82 NF-kappa B DTGs code secretory proteins, which include CCL2 and DIM that have already been used as HCC markers. Finally, the NF-kappa B DTGs were further confirmed by detecting the NF-kappa B binding and expression of 14 genes with ChIP-PCR and RT-PCR. This ...
Microarray gene and chemokine protein expression profiling showed a marked pro-inflammatory NF-κB signature, and activated podocytes secreting CCL2 and CCL5 induced macrophage migration in transwell assays. Neutralization of TNFR2 on podocytes with blocking antibodies abrogated NF-κB activation and the ...
TNF alpha receptors are constitutively overexpressed in tumor cells, correlating to sustain elevated NF kappa B and monocyte chemotactic protein-1 (MCP-1/CCL2) expression. The elevation of CCL2 evokes aggressive forms of malignant tumors marked by tumor associated macrophage (TAM) recruitment, cell ...
NF-κB是对有害细胞刺激的第一反应者。已知的NF-κB通路激活的炎症与免疫相关的因子有很多，包括促炎细胞因子（TNF-α、IL-1β、IL-6、IL-12、趋化因子(CXCL8（IL-8）、CCL2（MCP-1）、CCL5（RANTES）)、免疫受体（CD80/CD86）、抗原提呈分子（MHC I/II类分子）等。细胞存活与凋亡调控基因如：抗凋亡蛋...