Rna-Seg Atlas則是目前有提供RNA-seq expression profiles的資料庫,但是其只含有一個data sets,11個檢體。 相對地,這次台灣清華大學建置的Cancer RNA-Seq Nexus資料庫裡頭有54組人類的癌細胞RNA-Seq data sets,且為phenotyp -genotype分類好的。另一方面,提供良好的視覺好網頁操作,可以用來看coding-transcript/lncRNA...
肿瘤转录组数分析CRN:Cancer RNA-Seq Nexus 2017-12-28 16:46 −... nkwy2012 0 1415 RNA-seq表达数据之样本PCA分析 2019-11-26 19:24 −## Principal component analysis (PCA) 分析 主成分分析(PCA)帮助我们归纳总结和可视化数据集中的信息,这些数据包含由多个相互关联的变量描述的个体 / 观察主成分...
http://syslab4.nchu.edu.tw/index.jsp
Cancer RNA-Seq Nexus: A database of phenotype-specific transcriptome profiling in cancer cellsdoi:10.1093/nar/gkv1282Jianrong LiChuan Hu SunWenyuan LiChun Chi Liu
(d), and P300 (e) ChIP-qPCR of indicated cell lines using primer amplifying e1 of ANLN SE.nof independent experiments is indicated by scatter dots.fmRNA expression levels of ANLN, data from Cancer RNA-seq Nexus. TNBCn = 42 samples, Normal tissuen = 21 samples adjacent to TNBC...
[74]. The origin and dynamics of monocyte-derived macrophages and self-maintained tissue-resident macrophages were further investigated in a mouse model of lung adenocarcinoma via a rigorous genetic approach combined with single-cell RNA sequencing (scRNA-seq) and lineage tracing. This study shows ...
[74]. The origin and dynamics of monocyte-derived macrophages and self-maintained tissue-resident macrophages were further investigated in a mouse model of lung adenocarcinoma via a rigorous genetic approach combined with single-cell RNA sequencing (scRNA-seq) and lineage tracing. This study shows ...
Intrigued by the nexus between cytokine signalling and transcriptional control, we postulate that the IL-11 autocrine loop is a determinant of docetaxel resistance in prostate cancer via the JAK1/STAT4 signalling axis. This investigation delineates the molecular choreography of this resistance mechanism...
Differential gene and transcript expression levels from the RNA sequences were examined using TopHat and Cufflinks. The gene expression level was determined using the FPKM method. We applied the DESeq algorithm to screen out the differentially expressed genes between two groups as described in the ...
As the role of RNA modification in gene expression regulation and human diseases, the “epitranscriptome” has been shown to be an important player in regulating many physiological and pathological processes. Meanwhile, the phenomenon of cancer drug resistance is becoming more and more frequent, especi...