而清華大學所建立的RNA-seq癌症資料庫:RNA-Seq Nexus, 是第一個擁有以上所有特性的資料庫,其有非常好的網路操作介面,且是開放給所有人可以用來做資料探勘等等的研究,是在做癌症研究或是精準醫療的科學家可以使用看看的。 這二十年來的基因表現研究都是以microarray技術為基底所建立的,像是Oncomine、NextBio、GCOD...
Cancer RNA-Seq Nexus: A database of phenotype-specific transcriptome profiling in cancer cellsdoi:10.1093/nar/gkv1282Jianrong LiChuan Hu SunWenyuan LiChun Chi Liu
肿瘤转录组数分析CRN:Cancer RNA-Seq Nexus 2017-12-28 16:46 −... nkwy2012 0 1415 RNA-seq表达数据之样本PCA分析 2019-11-26 19:24 −## Principal component analysis (PCA) 分析 主成分分析(PCA)帮助我们归纳总结和可视化数据集中的信息,这些数据包含由多个相互关联的变量描述的个体 / 观察主成分...
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Intrigued by the nexus between cytokine signalling and transcriptional control, we postulate that the IL-11 autocrine loop is a determinant of docetaxel resistance in prostate cancer via the JAK1/STAT4 signalling axis. This investigation delineates the molecular choreography of this resistance mechanism...
Website:http://seqanswers.com/forums/showthread.php?t=43 Note: Examples Name:Cufflinks Comment:Cufflinks assembles transcripts, estimates their abundances, and tests for differential expression and regulation in RNA-Seq samples. It accepts aligned RNA-Seq reads and assembles the alignments into a ...
A computational approach used in single-cell RNA sequencing (scRNA-seq) to construct a pathway of how cells traverse though different states over time. Tumour mesenchyme Vastly heterogeneous non-epithelial, non-endothelial, non-leukocyte elongated cells lacking mutations found in cancer cells. Rights ...
Over the past few decades, cancer immunotherapy has experienced a significant revolution due to the advancements in immune checkpoint inhibitors (ICIs) and adoptive cell therapies (ACTs), along with their regulatory approvals. In recent times, there has been hope in the effectiveness of cancer vacci...
7A RNA-IMC study of metastatic melanoma that identifies local patches of chemokine-secreting cells together with the phenotypes of the cells in the surrounding milieus. ArticleCASPubMed Lin, J. R. et al. Multiplexed 3D atlas of state transitions and immune interaction in colorectal cancer.Cell ...
Single-cell RNA-seq highlights intra-tumoral heterogeneity and malignant progression in pancreatic ductal adenocarcinoma. Cell Res. 29, 725–738 (2019). Article CAS PubMed PubMed Central Google Scholar Puram, S. V. et al. Single-cell transcriptomic analysis of primary and metastatic tumor ...