C-type lectin-like receptor 2 (CLEC-2) has been identified as a receptor for a platelet-activating snake venom, rhodocytin. CLEC-2 elicits powerful platelet activation signals in a manner dependent on Src, Syk kinases, and phospholipase C纬2, similar to the collagen receptor glycoprotein (...
C-Type Lectin-Like Receptor 2 (CLEC-2) 下载积分: 8950 内容提示: Chapter 6C-Type Lectin-Like Receptor 2 (CLEC-2)Katsue Suzuki-InoueAbstract C-type lectin-like receptor 2 (CLEC-2) has been identif i ed as a receptorfor a platelet-activating snake venom, rhodocytin. CLEC-2 elicits ...
C-type lectin-like receptors in peptide-specific HLA class I-restricted cytotoxic T lymphocytes: differential expression and modulation of effector functions in clones sharing identical TCR structure and epitope specificity. Eur. J. Immunol. 28, 1134-1142 (1998)....
Galectin-3 has also been shown to associate with TLR-2, and the data indicate that it plays asimilar role in The fungal pattern recognition receptor, Dectin-1, and the associated cluster ofC-type lectin-like receptors. Dectin-1 is a major beta-glucan receptor on macrophages. doi...
The Dectin-2 family of C-type lectin-like receptors: an update New discoveries reveal crucial roles for the Dectin-2 family in many aspects of the immune response.Myeloid and non-myeloid cells express members of the C-... K Bernhard,JA Willment,GD Brown - 《International Immunology》 被引...
C-type lectin-like receptor-2 (CLEC-2) is a member of the C-type lectin superfamily of cell surface receptors. The first confirmed endogenous and exogenous ligands of CLEC-2 are podoplanin and rhodocytin, respectively. CLEC-2 is expressed on the surface of platelets, which participates in...
C-type lectin receptors (CLRs) comprise a large family of receptors that bind to carbohydrates in a calcium-dependent manner.
C-type lectins bind carbohydrates in a Ca2+-dependent manner and C-type lectin-like molecules bind either carbohydrates, polypeptide ligands or both. C-type lectins and C-type lectin-like receptors are involved in a multitude of biological processes, including cell migration, antigen uptake and pr...
PRRs include the archetypical Toll‑like receptors (TLRs), as well as non‑TLRs such as intracellular nucleotide‑ binding domain and leucine‑rich‑repeat‑containing family (NLRs), retinoic acid‑inducible gene I (RIG‑I)‑ like receptors and C‑type lectin receptors (CLRs)2. ...
Signals from these receptors impact myeloid ... D Sancho,RES Caetano - 《Current Opinion in Immunology》 被引量: 121发表: 2013年 C‐type lectin‐like receptors on myeloid cells Host defence against pathogens requires the recognition of conserved microbial molecules, or 'pathogen-associated molecular...