内容提示: Chapter 6C-Type Lectin-Like Receptor 2 (CLEC-2)Katsue Suzuki-InoueAbstract C-type lectin-like receptor 2 (CLEC-2) has been identif i ed as a receptorfor a platelet-activating snake venom, rhodocytin. CLEC-2 elicits powerful plateletactivation signals in a manner dependent on ...
C-type lectin-like receptor-2 (CLEC-2) is a member of the C-type lectin superfamily of cell surface receptors. The first confirmed endogenous and exogenous ligands of CLEC-2 are podoplanin and rhodocytin, respectively. CLEC-2 is expressed on the surface of platelets, which participates in...
ChemicalBook provide Chemical industry users with CLEC2L, NT (CLEC2L, C-type lectin domain family 2 member L) (MaxLight 750)() Boiling point Melting point,CLEC2L, NT (CLEC2L, C-type lectin domain family 2 member L) (MaxLight 750)() Density MSDS Formula U
Macrophages are integral to the pathogenesis of atherosclerosis, but the contribution of distinct macrophage subsets to disease remains poorly defined. Using single cell technologies and conditional ablation via a LysMCre+ Clec4a2flox/DTR mouse strain, w
(L-SIGN, LSECtin, CLEC10A) have been reported to interact with viral glycans to facilitate virus spreading and exacerbates inflammatory reactions. Moreover, spleen tyrosine kinase (Syk)-coupled C-type lectin member 5A (CLEC5A) has been shown as the pattern recognition receptor for members of...
(PAMPs). Especially, dectin-1 is critical for recognition of fungal β-glucan and has a collaborative effect with Toll-like receptor (TLR) 2 on yeast-induced activation signals, whereas DC-SIGN is involved in the recognition of a variety of microorganisms including viruses, bacteria, fungi, ...
C-Type lectin-like receptor LOX-1 promotes dendritic cell-mediated class-switched B cell responses. Immunity 41, 592–604 (2014). Article PubMed PubMed Central CAS Google Scholar Dambuza, I. M. & Brown, G. D. C-type lectins in immunity: recent developments. Curr. Opin. Immunol. 32C...
C-Type Lectin-Like Receptor (CLEC) 2, the Ligand of Podoplanin, Induced Dynamic Change of F-Actin Filaments in Podocytes Severe burns are associated with massive tissue destruction and cell death where nucleus histones and other damage-associated molecular patterns are releas... Keiko Tanaka,Taiji...
4.2.2 髓性细胞表面非经典C型凝集素 相比于NK细胞表面非经典C型凝集素,这群表达于髓性细胞表面的 NK 样 C 型凝集素样受体 (NK-likeC-type lectin receptor,NKCL)识别的配体更加广泛,行使的功能更加多样。常见的 NKCL包括 Dectin-1、LOX-1、CLEC-1、CLEC-2 和 MICL 等,这些凝集素也常表达于内皮...