C-type lectin like receptors (CLRs), play an important role in immune functions of the organisms. In chicken, B-NK and B-Lec genes encode CLRs that contain C-type lectin like domain. Polymorphism in CDS of B-NK and B-Lec genes were investigated in Ghagus, Nicobari and W...
form a large family containing soluble and membrane-bound proteins. Among them, those expressed on phagocytes and working as pathogen pattern-recognition receptors were designated as C-type lectin receptors (CLRs), in accordance with Toll-like receptors (TLRs), NOD-like receptors (NLRs),...
C-Type Lectin Receptors C-type lectin receptors (CLRs) comprise a large family of receptors that bind to carbohydrates in a calcium-dependent manner. The lectin activity of these receptors is mediated by conserved carbohydrate-recognition domains (CRDs). On the basis of their molecular structure, ...
Galectin-3 has also been shown to associate with TLR-2, and the data indicate that it plays asimilar role in The fungal pattern recognition receptor, Dectin-1, and the associated cluster ofC-type lectin-like receptors. Dectin-1 is a major beta-glucan receptor on macrophages. doi...
PRRs include the archetypical Toll‑like receptors (TLRs), as well as non‑TLRs such as intracellular nucleotide‑ binding domain and leucine‑rich‑repeat‑containing family (NLRs), retinoic acid‑inducible gene I (RIG‑I)‑ like receptors and C‑type lectin receptors (CLRs)2. ...
Pathogen recognition by C-type lectin receptors (CLRs) expressed by dendritic cells is important not only for antigen presentation, but also for the induction of appropriate adaptive immune responses via T helper (TH) cell differentiation. CLRs act either by themselves or in cooperation with other ...
Similar to the killer lectin-like receptors whose genes are clustered in this complex, most of the CLRs induce activating or regulatory signal cascades in response to distinct pathogen- or self-derived components, through the immunoreceptor tyrosine-based activating or inhibitory motif, respectively. ...
CLRs are a group of transmembrane proteins with one or more carbohydrate recognition domains (CRDs) or C-type lectin-like domains (CTLDs) that are involved in calcium-dependent recognition of pathogen surface carbohydrates [21]. From: Non-coding RNA Research, 2023 ...
C-type lectin receptors (CLRs) comprise a large family of receptors that bind to carbohydrates in a calcium-dependent manner. CLRs include the Dendritic cell-associated C-type lectin-1 (Dectin-1), Dectin-2, macrophage-inducible C-type lectin (Mincle), DC-specific intercellular adhesion molecule...
C-type lectin receptors (CLRs). Receptors that recognize carbohydrates expressed by microorganisms, as well as endogenous glycoproteins. Some CLRs function as pattern-recognition receptors, whereas others function as adhesion receptors. The recognition of microorganisms by CLRs on antigen-presenting cells ...