C-type lectin-like receptor 2 (CLEC-2) has been identified as a receptor for a platelet-activating snake venom, rhodocytin. CLEC-2 elicits powerful platelet activation signals in a manner dependent on Src, Syk kinases, and phospholipase C纬2, similar to the collagen receptor glycoprotein (...
C-Type Lectin-Like Receptor 2 (CLEC-2) 下载积分: 8950 内容提示: Chapter 6C-Type Lectin-Like Receptor 2 (CLEC-2)Katsue Suzuki-InoueAbstract C-type lectin-like receptor 2 (CLEC-2) has been identif i ed as a receptorfor a platelet-activating snake venom, rhodocytin. CLEC-2 elicits ...
Soluble forms of several platelet membrane proteins are released upon platelet activation; however, the soluble form of C-type lectin-like receptor 2 (sCLEC-2) has not yet been fully investigated. Western blotting with an anti-CLEC-2 antibody showed that sCLEC-2 was released from washed ...
C-type lectin-like receptor-2 (CLEC-2) is a member of the C-type lectin superfamily of cell surface receptors. The first confirmed endogenous and exogenous ligands of CLEC-2 are podoplanin and rhodocytin, respectively. CLEC-2 is expressed on the surface of platelets, which participates in...
英文名称:C-Type Lectin-Like Receptor-2 (CLEC2) Antibody,中文名称:C型凝集素样受体2(CLEC2)抗体,产品货号:Catalogue No: abx430499,CLEC2抗体是一种抗CLEC2的山羊多克隆抗体。靶点CLEC2反应性人宿主山羊克隆性多克隆检测应用P-ELISA
C-type lectin-like receptor-2 (CLEC-2) is a nonclassical C-type lectin receptor, which is mainly expressed on platelets and granulocytes. Under stimulation of the snake venom protein rhodocytin and transmembrane sialoglycoprotein podoplanin, it can form a dimer through YXXL motif in the cytoso...
et al. C-Type lectin-like receptor 2 promotes hematogenous tumor metastasis and prothrombotic state in tumor-bearing mice. J. Thromb. Haemost. 15, 513–525 (2017). Article PubMed CAS Google Scholar Ku, A. W. et al. Tumor-induced MDSC act via remote control to inhibit L-selectin-...
Soluble forms of several platelet membrane proteins are released upon platelet activation; however, the soluble form of C-type lectin-like receptor 2 (sCLEC-2) has not yet been fully investigated. Western blotting with an anti-CLEC-2 antibody showed that sCLEC-2 was released from washed ...
every mature NK cell should bear at least one type of dominant inhibitory receptor for a self MHC class I product, thus preventing autoreactivity against normal cells. Recognition of H-2 products is mediated by members of the Ly-49 C-type lectin family (Yoxoyama1995). In humans several inhi...