Using a yeast two-hybrid screen with menin as the bait, we have identified the transcription factor JunD as a direct menin-interacting partner. Menin did not interact directly with other Jun and Fos family members. The menin-JunD interaction was confirmed in vitro and in vivo. Menin ...
Taken together, these data suggest a potential role for the AP1 transcription factors in the maintenance of the peripheral taste system. AP1 transcription factors are downregulated in CV/Fol taste cells from 6-month-old mice. We validated the differences in the expression of c-Fos, c-Jun and ...
transcriptionAP1junfostransformationGrowth factors activate cascades of intracellular events, some of which result in altered gene expression. A series of recent discoveries have highlighted the role of the transcription factor AP1 as a mediator of the effects of growth factors, as well as those of ...
Using a yeast two-hybrid screen with menin as the bait, we have identified the transcription factor JunD as a direct menin-interacting partner. Menin did not interact directly with other Jun and Fos family members. The menin–JunD interaction was confirmed in vitro and in vivo. Menin ...
There are comments on PubPeer for publication: Curcumin Suppresses AP1 Transcription Factor-dependent Differentiation and Activates Apoptosis in Human Epidermal Keratinocytes (2007)
aThe AP1 transcription factor network jun(c-jun, junB, junD) and fos (c-fos, FosB, Fra-1, Fra-2) network AP1副本因素网络junD 6月(c6月, junB,)和fos (cfos, FosB, Fra1, Fra2)网络[translate]
The activated JNKs translocate to the nucleus where they phosphorylate and activate transcription factors such as c-Jun. The activated c-Jun forms homodimers or heterodimers with fos family proteins which bind to the activator protein-1(AP1) response element and induce target gene transcription. ...
Angel, A. Szabowski / Biochemical Pharmacology 64 (2002) 949±956 skin wounds interstitial collagenase (MMP-1, MMP-13), MMP-9, MMP-3, MMP-10 and their physiological inhibitor TIMP-1 are strongly induced showing a unique spatial and temporal transcription pattern [44]. Tissue culture as ...
Although little native AtAAP1 transcription was present in the leaves, constitutive expression of AtAAP1 in plants significantly increased the ability of the leaf mesophyll protoplasts to take up CAP-Ala-1. The observations supported the possibility of exploiting AtAAP1 as a component of a novel ...