(1998). AP-1 transcription factors: Short- and long-term modulators of gene expression in the brain. Int. Rev. Neurobiol. 42, 169-197.Pennypacker K. 1998. AP-1 transcription factors: short and long-term modulators of gene expression in the brain. Int Rev Neurobiol 42:169 - 197....
Activator protein-1 (AP-1) is an inducible transcription factor, and is comprised of multiple protein complexes that include the gene products of the fos and jun gene families. Numerous cellular and viral genes contain AP-1 binding sites within their promoters and, accordingly, AP-1 has been ...
Molecular cloning and characterization of transcription factor AP-1 gene in Apis cerana cerana ( Hymenoptera: Apidae) 【Aim】The objective of this study is to clone the cDNA sequence of transcription factor AP-1 gene( Acc AP-1) from Apis cerana cerana and to explore its ex... XP Chi,W ...
Fig. 2.The interactions of Jun and Fos proteins. The transcription factor AP-1 is formed by dimerization of Jun proteins (c-Jun, JunB and JunD) or heterodimerization of a Jun protein with a Fos protein (c-Fos, FosB, Fra-1 and Fra-2). AP-1 binds primarily to the 12-O-tetradecanoylp...
Transcription factor AP-1 is a dimer formed by DNA-binding proteins of the Jun, Fos, and ATF families (activating transcription factor). AP-1 mediates the cell response to growth factors, cytokines, neurotransmitters, and other intercellular signaling molecules. Regulation of AP-1 activity involves...
These genes are known downstream targets of the JNK pathway and we demonstrate that their expression not only depends on the transcription factor AP-1, but also on Ets21C suggesting a cooperative transcriptional activation mechanism. Taken together we show that Ets21C is a crucial player in ...
例句They're sometimes called transcription factors and this is an example of a transcription factor that is itself activated or turned on by the presence of a steroid.它们被称为转录因子,转录因子的一个例子就是,能够自激活或被激素激活。
In ovine pars tuberalis cells which express high affinity Mel 1a melatonin receptors, the ability of melatonin to directly stimulate or inhibit AP-1 transcription factor gene expression was studied. Effects of melatonin upon mRNA expression by forskolin, serum and IGF-1 were also investigated. Northe...
For instance, transcription factor AP-1 promotes the expression of PD-L1 in Hodgkin lymphomas by binding to the AP-1-responsive enhancer in the PD-L1 gene14, and HIF-2α targeted PD-L1 in renal cell carcinoma15. In TNBC, the protein expression and mRNA level of PD-L1 are higher than ...
c-Fos: an AP-1 transcription factor with an additional cytoplasmic, non-genomic lipid synthesis activation capacity. Biochim Biophys Acta 2014; 1841: 1241–1246. 28. Malnou CE, Salem T, Brockly F, Wodrich H, Piechaczyk M, Jariel-Encontre I. Heterodimerization with Jun family members ...