Despite their extremely low abundance (approximately three orders of magnitude lower than in PSCs), OCT4A proteins bound to the promoter/enhancer regions of the AP-1 transcription factor subunit c-FOS gene and critically regulated its transcription. Knocking out OCT4A in somatic cancer cells led...
FOS(Fos proto-oncogene, AP-1 transcription factor subunit) fos基因家族由4个成员组成:fos、fosb、fosl1和fosl2。这些基因编码亮氨酸拉链蛋白,可与Jun家族的蛋白质二聚,从而形成转录因子复合物AP-1。因此,fos蛋白被认为是细胞增殖、分化和转化的调节因子。在某些情况下,fos基因的表达也与凋亡细胞死亡有关。The ...
ANuclear Factor-κB NF-κB is a pleiotropic transcription factor found in nearly all animal cell types. In the cell's normal state, NF-κB stays in an inactive state in the cytoplasm as a heterotrimer consisting of the subunits p50, p65, and the inhibitory subunit IκBα. In response...
JUN(Jun proto-oncogene, AP-1 transcription factor subunit) 该基因是禽肉瘤病毒17的假定转化基因。它编码一种与病毒蛋白高度相似的蛋白质,并与特定靶DNA序列直接相互作用以调节基因表达。这个基因是无内含子的,被定位到1P32-P31,一个涉及人类恶性肿瘤易位和缺失的染色体区域。This gene is the putative ...
(bZIP) domain and can interact with other bZIP proteins, such as MAF and ATF, which allows them to target the cAMP response element (CRE), and with the p65 subunit of nuclear factor κB (NF-κB). A dominant-negative mutant form of c-Jun (TAM67) interacts with any of the three Jun...
产品名称 JunD Proto-Oncogene, AP-1 Transcription Factor Subunit (JUND) ELISA Kit 产品货号 Catalogue No: abx595335 产品价格 现货询价,电话:010-67529703 产品规格 Available Options * Size: 96 tests 产品品牌 abbexa 产品概述 JunD细胞ELISA试剂盒是一种基于细胞的ELISA试剂盒。待测细胞应...
JUN (Jun Proto-Oncogene, AP-1 Transcription Factor Subunit) is a Protein Coding gene. Diseases associated with JUN include Sarcoma and Pertussis. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Common Cytokine Recept...
JUN is the putative transforming gene of avian sarcoma virus 17. It encodes a protein(Jun proto-oncogene, AP-1 transcription factor subunit) which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. JUN is intronles...
ELISA试剂盒 一抗 二抗 CLIA试剂盒 同型对照 蛋白质和肽 试剂和工具 RNA干扰产品 小分子 产品详情 中文名称:JUND原癌基因,AP-1转录因子亚基(JUND)抗体 英文名称:JunD Proto-Oncogene, AP-1 Transcription Factor Subunit (JUND) Antibody 品牌:Abbexa
Activating protein 1 (AP-1) is a transcription factor composed of several protein families, Jun proteins and Fos proteins are the components of AP-1. AP-1