Signaling pathwayApoptosisIn mammalian cells, apoptotic and anti-apoptotic pathways may be investigated using a variety of biochemical, molecular, and genetic approaches. Retrovirus mediated genetic screens have proven a powerful tool in mapping out the network of players in a number of signaling ...
摘要: Objective – To review the human and veterinary literature on the biology of apoptosis in health and disease.关键词:cancer caspases cell death intrinsic pathway sepsis DOI: 10.1111/j.1476-4431.2008.00363.x 年份: 2008 收藏 引用 批量引用 报错 分享 全部来源 免费下载 求助全文 Wiley ...
Tumour cell survival signalling by the ERK1/2 pathway Cell Death Differ., 16 (2009), pp. 368-377 Google Scholar [156] V. Duronio The life of a cell: apoptosis regulation by the PI3K/PKB pathway Biochem. J., 415 (2008), pp. 333-344 Google Scholar [157] F.H. Igney, P.H. K...
The aims of this study were as follows: (1) to test whether the signaling mechanisms underlying the proapoptotic activity of miR-34a are associated with the SIRT1/p66shc pathway in NAFLD; (2) to investigate whether CA activates SIRT1/p66shc by inhibiting miR-34a; and (3) to elucidate ...
The result suggested that DHC plays a potent role in anticervical cancer in multiple biological aspects through PI3K/Akt signaling pathway, independently of HPV infection. This finding surely adds new knowledge to understand the role of DHC in fighting cancers. 展开 ...
3.The Signal Transduction Pathway of Glucocorticoid-induced Anti-apoptosis in Tumor Cells;糖皮质激素诱导肿瘤细胞抗凋亡的信号转导通路 英文短句/例句 1.Experimental Studies of Neuroprotection Combined Antiapoptosis Therapy;神经保护联合抗凋亡治疗的实验研究 2.The Anti-apoptotic Effect on PC12 Cells Induced ...
Bioinformatics analysis showed that apoptosis and the phosphoinositide 3-kinase/protein kinase B (PI3K-Akt) signaling pathway were the main signaling pathways of XYS. In vitro experiments showed that XYS could improve the effect of OGD/R on PC12-cell activity (EC50 = 0.43 mg/mL) and inhibit ...
Correction: TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β- induced rat osteoarthr... Correction: TNF/TNFR signal transduction pathway-mediated anti- apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β- induced ...
Induction and Intracellular Regulation of Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Mediated Apotosis in Human Malignant Glioma Cells This caspase-8-induced apoptotic cascade is regulated by intracellular PED/PEA-15, but not by cFLIP or decoy receptors. This pathway may be exploit...
Correction: TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β- induced rat osteoarthr... Correction: TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1尾-induced rat...