Bioinformatics DLX4 homeoprotein promotes PI3K/Akt anti-apoptosis pathway in ER negative breast cancer cells through upregulation of VEGFA THE GEORGE WASHINGTON UNIVERSITY Sidney Fu WuWeiweiThe progression of breast cancer has been linked to a splice variant of DLX4 homeobox transcription factor, DLX4...
Siveen KS, Sikka S, Surana R, Dai X, Zhang J, Kumar AP, Tan BKH, Sethi G, Bishayee A (2014) Targeting the STAT3 signaling pathway in cancer: role of synthetic and natural inhibitors. Biochim Biophys Acta 1845:136–154. doi:10.1016/j.bbcan.2013.12.005 CAS PubMed Google Scholar ...
The aims of this study were as follows: (1) to test whether the signaling mechanisms underlying the proapoptotic activity of miR-34a are associated with the SIRT1/p66shc pathway in NAFLD; (2) to investigate whether CA activates SIRT1/p66shc by inhibiting miR-34a; and (3) to elucidate ...
The Akt signaling pathway is a prominent intracellular signal transduction pathway that regulates cellular survival and functions [10]. Akt consists of three isoforms i.e., Akt1, Akt2 and Akt3 that are closely related to each other [11]. Amongst the three isoforms, Akt1 appears to be the ...
摘要: Objective – To review the human and veterinary literature on the biology of apoptosis in health and disease.关键词:cancer caspases cell death intrinsic pathway sepsis DOI: 10.1111/j.1476-4431.2008.00363.x 被引量: 116 年份: 2008
In addition to innate immunity,apoptosisalso acts as an important antiviral mechanism by eliminating infected cells. Thus, inhibition of apoptosis is also of critical importance for HCMV. Among HCMV-encoded proteins, UL36 has long been identified as an inhibitor of extrinsic apoptotic pathway by di...
The mitochondrial death pathway and cardiac myocyte apoptosis. Circulation Research. 2004;95:957–63. Article PubMed CAS Google Scholar Gottlieb RA, Burleson KO, Kloner RA, Babior BM, Engler RL. Reperfusion injury induces apoptosis in rabbit cardiomyocytes. J Clin Invest. 1994;94:1621–8. ...
(PI3-K/AKT)pathway,insulin/ insulin-like growth factor pathway,mitogen activated protein kinase pathway and nuclear factor κB pathway.Insulin prevents activation of caspase-3 and inhibits the apoptosis of retinal neurons by PI3-K/AKT pathway.But the mechanisms about anti-apoptosis activity of ...
大鼠急性胰腺炎中核因子NF-κB抗凋亡机制的研究 3. The Signal Transduction Pathway of Glucocorticoid-induced Anti-apoptosis in Tumor Cells; 糖皮质激素诱导肿瘤细胞抗凋亡的信号转导通路 更多例句>> 6) apoptosis/drug effects 细胞凋亡/药物作用补充
3.The Signal Transduction Pathway of Glucocorticoid-induced Anti-apoptosis in Tumor Cells;糖皮质激素诱导肿瘤细胞抗凋亡的信号转导通路 英文短句/例句 1.Experimental Studies of Neuroprotection Combined Antiapoptosis Therapy;神经保护联合抗凋亡治疗的实验研究 2.The Anti-apoptotic Effect on PC12 Cells Induced ...