Infection and immunityYilmaz O, Jungas T, Verbeke P, Ojcius DM. Activation of the phosphatidylinositol 3-kinase/Akt pathway contributes to survival of ... Ozlem,Yilmaz,Thomas,... - 《Infection & Immunity》 被引量: 210发表: 2004年 Cellular Inhibitors of Apoptosis Proteins cIAP1 and cIAP2 Ar...
The value of such a book as this is rather that you might hope to find some interesting information that would otherwise have eluded you, and in this I for one was not disappointed. For example, I found there is evidence for proteases and the ubiquitin pathway in apoptosis, and I learned...
The intrinsic (“mitochondrial”) cell death pathway is activated in response to cellular stresses, such as DNA damage or growth factor deprivation, and is regulated by the BCL-2 family of proteins1. In mammals, this family consists of opposing pro-survival and pro-apoptotic members which are ...
There are at least two broad signaling pathways that lead to apoptosis: the intrinsic pathway of apoptosis and the extrinsic pathway of apoptosis. The extrinsic pathway of apoptosis begins outside a cell, when conditions in the extracellular en...
Cytotoxic elimination of dendritic cells (DC) in lymphoid tissue represents an important pathway of immune regulation. However, the mechanism of DC removal is still controversial since mature DC are insensitive to death receptor﹎ediated killing and other surface or soluble molecules mediating DC death...
Our laboratory has previously shown that after immunization with a strain of Salmonella typhimurium, SL3235, made avirulent by a blockage in the pathway of... AS Macfarlane,MG Schwacha,TK Eisenstein - 《Infection & Immunity》 被引量: 236发表: 1999年 Immunogenicity induced in vivo by DIC in ...
APOPTOSOME PATHWAY A pathway of caspase activation that requires release of cytochromecfrom the mitochondria. PLAQUE ASSAY An assay that allows visualization of the cytopathic effect of viruses or bacteria in a monolayer of host cells. The plaque centre lacks cells due to infection-induced lysis. ...
Cell death in the pathogenesis of heart disease: mechanisms and significance Annu. Rev. Physiol., 72 (2010), pp. 19-44 Google Scholar [9] S. Gupta, G.E. Kass, E. Szegezdi, B. Joseph The mitochondrial death pathway: a promising therapeutic target in Diseases J. Cell. Mol. Med., ...
(GST); Lane 3: washed liquid; Lane 4: eluted liquid. (e) The activity of rEsIAP1 was detected with caspase-3 activity assay kit. (f) Model forEsIAP1 involvement in apoptosis pathway. A. hydrophilacould activate caspase-mediated apoptosis pathway to initiate the activity ofEsCaspase-3/7-...
M. et al. Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-κB pathway. Immunity 7, 821–830 (1997). Article CAS PubMed Google Scholar MacFarlane, M. et al. Identification and molecular cloning of two novel receptors for ...