Apoptosis: A review of pro‐apoptotic and anti‐apoptotic pathways and dysregulation in disease M.A. O'Brien, R. Kirby, Apoptosis: a review of pro-apoptotic and anti-apoptotic pathways and dysregulation in disease, J. Vet. Emerg. Crit. Care ... M O'Brien,R Kirby - 《Journal of Veterin...
The mitochondrial pathway in yeast apoptosis Apoptosis, 12 (2007), pp. 1011-1023 Google Scholar [262] F. Madeo, D. Carmona-Gutierrez, J. Ring, S. Buttner, T. Eisenberg, G. Kroemer Caspase-dependent and caspase-independent cell death pathways in yeast Biochem. Biophys. Res. Commun., 382...
3.The Signal Transduction Pathway of Glucocorticoid-induced Anti-apoptosis in Tumor Cells;糖皮质激素诱导肿瘤细胞抗凋亡的信号转导通路 英文短句/例句 1.Experimental Studies of Neuroprotection Combined Antiapoptosis Therapy;神经保护联合抗凋亡治疗的实验研究 2.The Anti-apoptotic Effect on PC12 Cells Induced ...
Disruption of MMI is a key step of the intrinsic pathway of apoptosis. Following 24 h of lapatinib treatment, the single knockdown cell lines had reduced MMI compared with the controls and suppression of both KLF4/5 produced an additive effect. Supporting an impact of KLF4/5 on the ...
BCL-2 family proteins are central regulators of mitochondrial apoptosis and validated anti-cancer targets. Using small cell lung cancer (SCLC) as a model, we demonstrated the presence of differential addiction of cancer cells to anti-apoptotic BCL-2, BCL-XLor MCL-1, which correlated with the ...
The E2F1 transcription factor can promote proliferation or apoptosis when activated, and is a key downstream target of the retinoblastoma tumour suppressor... EJ Morris,JY Ji,F Yang,... - 《Nature》 被引量: 533发表: 2008年 Retinoic acid–induced apoptotic pathway in T-cell lymphoma: Identifica...
Osteoarthritis chondrocytes die by apoptosis. A possible pathway for osteoarthritis pathology Arthritis Rheum, 41 (1998), pp. 284-289 View in ScopusGoogle Scholar 3 H.A. Kim, Y.W. Song Apoptotic chondrocyte death in rheumatoid arthritis Arthritis Rheum, 42 (1999), pp. 1528-1537 View in Scopu...
Similarly, our findings that sustained gastrin treatment is required for the sustained activation of the PKC /ERK1/2-pathway as well as for PKC-dependent activation of anti-apoptosis (Figure 4), indicate that the duration of ERK1/2 activation translates duration of gastrin signalling into pro-...
Regulation of Caspase Expression and Apoptosis by Adenomatous Polyposis Coli The adenomatous polyposis coli (APC) gene, a member of the WNT pathway, has been shown to assign intestinal epithelial cells to a program of proliferation ... T Chen,I Yang,R Irby,... - 《Cancer Research》 被引量...
Bax is a pro-apoptotic Bcl-2 family protein and plays an important role in the mitochondria-mediated apoptosis pathway. It is a cytosolic protein and normally remains in the apoptotically inactive monomeric form; however, during apoptosis its conformational change causes homo-oligomerization and ...