Cancer Genome Sequencing Overview Whole genome sequencing (WGS) is a method of next generation sequencing that can provide comprehensive genomic data. Sequencing a cancer patient's whole genome may help researchers better understand the genetic components of cancer pathogenesis, including heritability and ...
Cancer ScienceNakagawa H, Fujita M (2018) Whole genome sequencing analysis for cancer genomics and precision medicine. Cancer Sci 109:513-522. https://doi.org/10.1111/cas.13505Nakagawa, H. and Fujita, M. (2018) Whole Genome Sequencing Analysis for Can- cer Genomics and Precision Medicine. ...
Whole-genome sequencing delivers a comprehensive view, ideal for discovery applications. Newer genome sequencers perform WGS more rapidly than ever.
Whole genome sequencing for childhood cancer in DenmarkRamneek Gupta
Comprehensive analysis of chromothripsis in 2,658 human cancers using whole‑genome sequencing Chromothripsis is found to be much more prevalent across cancers than previously thought, with a frequency of >50% in several cancer types. Tumour evolution ...
Circulating cell-free DNA (cfDNA) is becoming an increasingly important research sample to investigate circulating tumor DNA (ctDNA) for investigation of many cancer types. Usingwhole-genome next-generation sequencing(N...
Whole genome sequencing (WGS) is becoming the preferred method for molecular genetic diagnosis of rare and unknown diseases and for identification of actionable cancer drivers. Compared to other molecular genetic methods, WGS captures most genomic variat
In contrast to primary colorectal cancer (CRC) little is known about the genomic landscape of metastasized CRC. Here we present whole genome sequencing data of metastases of 429 CRC patients participating in the pan-cancer CPCT-02 study (NCT01855477). Un
As whole-genome sequencing for cancer genome analysis becomes a clinical tool, a full understanding of the variables affecting sequencing analysis output is required. Here using tumour-normal sample pairs from two different types of cancer, chronic lymph
Learn about what whole exome sequencing is, why it’s important, and how it’s furthering discoveries in cancer research.