Personalized blood tests for cancer that use whole‐genome sequencingpostoperative painsevere postoperative painbenzodiazepinesmorphine consumptionpostoperative care unitNo abstract is available for this article.doi:10.1002/cncr.25469Carrie PrintzJohn Wiley & Sons, LtdCancer...
Whole-genome sequencing (WGS) is becoming an increasingly important tool for detecting genomic variation. Blood derived DNA is the current standard for WGS for research or clinical purposes but may not always be feasible to acquire. The usability of DNA from saliva for WGS is not known. We com...
Blood lipids are heritable modifiable causal factors for coronary artery disease. Despite well-described monogenic and polygenic bases of dyslipidemia, limitations remain in discovery of lipid-associated alleles using whole genome sequencing (WGS), partly due to limited sample sizes, ancestral diversity, ...
sensitive, scalable purification from an expansive set of starting materials to help maximize process efficiency and downstream performance. This includes a broad range of kits for purifying genomic DNA from a variety of sam...
Whole genome sequencing (WGS) is becoming the preferred method for molecular genetic diagnosis of rare and unknown diseases and for identification of actionable cancer drivers. Compared to other molecular genetic methods, WGS captures most genomic variat
sensitive, scalable purification from an expansive set of starting materials to help maximize process efficiency and downstream performance. This includes a broad range of kits for purifying genomic DNA from a variety of sa...
For the resequencing and population genome analyses, we collected samples from Fennoscandian reindeer of the Muddusjärvi and Sallivaara herding cooperatives in northern Finland (n = 10 males, blood samples in EDTA tubes), Nenets reindeer from the Arkhangelsk region in northwest Russia (n ...
(GWAS) of common genetic variants and through exome sequencing. We conducted a whole-genome sequencing study of common, low-frequency and rare variants to associate genetic variations with blood metabolite levels using comprehensive metabolite profiling in 1,960 adults. We focused the analysis on ...
We performed WGS on matched tumor-blood samples from 92 cases and transcriptome sequencing on matched tumor-adjacent tissues from 90 of the same individuals. Clinical information and inferred TILs of 90 patients were listed in the Supplementary Table7. An additional 57 cases (matched tumor-blood) ...
Tumor sections (3–18 sections, contingent on the extent of necrosis) of 10 μM were used to prepare tumor DNA using the “AllPrep DNA/RNA/miRNA Universal Kit” (Cat. no 80224, Qiagen, Hilden, Germany) in line with the manufacturer’s protocol. Blood DNA was using the Blood DNA kit...