These bends are detectable at 30 degrees C but melt at 37 degrees C, the temperature at which the cells undergo phenotypic switching. We also show that pACYC184, a plasmid used as a reporter of temperature-induced changes in DNA supercoiling, has a single region of intrinsic bending detected...
"Senescent cells undergo widespread changes in gene expression needed to adapt their phenotype and functions," said Rugang Zhang, Ph.D., deputy director of The Wistar Institute Cancer Center, Christopher M. Davis Professor and leader of the Immunology, Microenvironment & Metastasis Program. "We poin...
Fig. 1: Effects of drug-induced expression of GALNTL5 protein in GC-2spd(ts) cells. A Western blotting with anti-GFP antibody. In the GC-2spd(ts) cell line with a chemically inducible expression vector for GALNTL5 tagged with GFP (GALNTL5-GFP/GC-2spd), GALNTL5 protein was detected...
How meiosis-1 is reductional division when parent and daughter cells have 46 chromosomes as in mitosis? What is the function of an ovum cell in multicellular organisms? What are the main organelles in a eukaryotic cell? What are human offspring called?
1D). Together this suggests that multinucleated cells that survive paclitaxel treatment are cell cycle arrested and less likely to undergo DNA damage-induced apoptosis than are mononucleated cells. Cells surviving paclitaxel treatment halt cycling and upregulate interferon response genes We assessed ...
The invention relates to a system for modelling ROS-induced apoptosis in a cell, said system comprising: a) the provision of a population of cells; b) the exposure of said cell population to one or more stimuli which lead the cell population to undergo ROS-induced apoptosis; c) optionally,...
whether in human cells or in mice, triggers the use of an upstream transcriptional start site of thezdhhc20gene, leading to the production of a N-terminally extended enzyme, ZDHHC20Long. The expression of ZDHHC20Longis also triggered following chemically induced colitis and pore-forming toxins,...
Deleting genes for protein kinase R-like endoplasmic reticulum kinase (PERK) or DNA damage-inducible transcript 3 (DDIT3, also known as CHOP) hampered the response of multiple myeloma cells to 2P-Im. The effect was similar to treatment with ISRIB, an integrated stress response inhibitor that ...
A monoclonal antibody (MoAb) H229(IgGl) was obtained by fusion between SP2/0, mouse myeloma cell line and spleen cells from BC3Fl mice immunized with HEL, a erythroleukemia cell line. MoAb H229 precipitated a 55 kilodalton(KD) molecule in reduced condition. It reacted with platelets and ...
Which of the following is a malignant tumor arising from pigment-producing cells of the skin? A. Nevus B. Melanoma C. Adenocarcinoma D. Lymphosarcoma Cancer Cancer is a general term referring to diseases in which cells in a...