What is p53 ?南京南瓜藤教育托福阅读背景知识(中文版)p53是存在人体细胞内的一种抗癌白质,它有抑制细胞生长及维持遗传物质完整性的功能。事实上,半数以上的癌症细胞内都有p53的突变,可见其在细胞生长控制上扮演了重要的角色。在正常状况下,p53的半衰期约只有30分钟,相当不稳定;然而当细胞经紫外线,离子化射线(如X光...
Expert commentary: Pertaining to the different expression of isoforms in different tumors, it is concluded that the clinical use of isoforms as prognostic and predictive biomarkers will be different depending on the cell type, the tissue origin of the tumors, the position of the TP53 mutation and...
Components of the Cell Membrane | Definition & Roles from Chapter 7 / Lesson 35 97K Learn about the structural components of cell membranes. Learn what the main component of the cell membrane is, and identify the roles that the components fulfill. Related...
If a woman has a new mutation in the p53 gene in a skin stem cell, what is the chance that she will pass that mutation on to her offspring (children)? A man who has type B blood (genotype: BB) is married to ...
Human hepatocellular carcinoma (HCC) is the fifth most common cancer and is associated with poor prognosis worldwide. The molecular mechanisms underlying the pathogenesis of HCC have been an area of continuing interest, and recent studies using next gene
Understanding the complexity of p53 in a new era of tumor suppression. Cancer Cell 2024, 42, 946–967. [Google Scholar] [CrossRef] [PubMed] [PubMed Central] Borchers, A.C.; Langemeyer, L.; Ungermann, C. Who’s in control? Principles of Rab GTPase activation in endolysosomal membrane...
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Cellular senescence is a state of stable cell cycle arrest. Cells remain metabolically active, but no longer divide or respond to growth-promoting stimuli.
Why do our chromosomes determine gender but a crocodile's gender is determined by temperature? What determines the specificity of a response of a cell to a steroid hormone and the nature of the response? How does sexuality ...