tyrosine-kinase-linked-receptors网络酪氨酸激酶活性的受体;信号者;酪氨酸激酶偶联受体 网络释义 1. 酪氨酸激酶活性的受体 具酪氨酸激酶活性的受体(tyrosine kinase-linked receptors)是结合细胞内酪氨酸激酶范围的膜受体。如胰岛素受体、胰岛素 …zh.wikipedia.org|基于10个网页 2. 信号者 ...受体本身无激酶活性,但...
Tec/Btk tyrosine kinases are members of a subgroup of Src tyrosine kinase family. They are reported to be activated in response to cytokines, such as IL-3 and IL-6. Janus kinases (JAKs) are known to associate with certain cytokine receptors, e.g. gp130, the signal transducing subunit of...
?种类 ◆酪氨酸激酶偶联受体(tyrosine kinase-linked receptors) ◆内源酶促活性受体(receptor with intrinsic enzymatic activity ),有很多种类型: ●受体鸟苷环化酶 (Receptor guanylyl cyclase); ●受体酪氨酸磷酸酶 (Receptor of tyrosine phophatase); ●受体酪氨酸激酶 (Receptor tyrosine kinase); ●受体丝氨酸...
Tyrosine kinase receptors are a type of receptor that consist of an external N-terminal segment and an internal C-terminal segment. When these receptors are activated, they stimulate the activity of the tyrosine kinase enzyme in the internal domain and cause the phosphorylation of specific molecules...
Angiotensin II and other hypertrophic stimuli mediated by G protein-coupled receptors activate tyrosine kinase, mitogen-activated protein kinase, and 90-kD... Many hypertrophic stimuli such as angiotensin II (Ang II) activate phospholipases through G protein-coupled receptors in cardiac myocytes. ...
Receptor tyrosine kinases (RTKs) are enzyme-linked receptors localized at the plasma membrane containing an extracellular ligand-binding domain, a transmembrane domain, and an intracellular protein–tyrosine kinase domain. In general, the ligands for RTKs are proteins such as IGF, epidermal growth fac...
Phospholipase Cgamma (PLCgamma) isoforms are regulated through activation of tyrosine kinase-linked receptors. The importance of growth factor-stimulated phosphorylation of specific tyrosine residues has been documented for PLCgamma1; however, despite the critical importance of PLCgamma2 in B-cell signal...
Protein-Tyrosine KinaseReceptorsAngiotensin血管紧张素ⅡDNA结合蛋白质类蛋白质酪氨酸激酶受体血管紧张素THE peptide angiotensin II is the effector molecule of the ... MB Marrero,B Schieffer,WG Paxton,... - 《Nature》 被引量: 2408发表: 1995年 The c-fms proto-oncogene product is related to the r...
Our findings indicate that GDNF and neurturin promote neuronal survival by signalling through similar multicomponent receptors that consist of a common receptor tyrosine kinase and a member of a GPI-linked family of receptors that determines ligand specificity. This is a preview of subscription content...
TYROSINE KINASE RECEPTORS AS FUNCTIONAL MARKERS AND THERAPEUTICAL TARGETS OF GLIOBLASTOMA STEM CELLS TYROSINE KINASE RECEPTORS AS FUNCTIONAL MARKERS AND THERAPEUTICAL TARGETS OF GLIOBLASTOMA STEM CELLSThis study aims to evaluate the role of Regorafenib, a ... C Boccaccio,FD Bacco,S Pellegatta,... -...