tyrosine-kinase-linked-receptors网络酪氨酸激酶活性的受体;信号者;酪氨酸激酶偶联受体 网络释义 1. 酪氨酸激酶活性的受体 具酪氨酸激酶活性的受体(tyrosine kinase-linked receptors)是结合细胞内酪氨酸激酶范围的膜受体。如胰岛素受体、胰岛素 …zh.wikipedia.org|基于10个网页 2. 信号者 ...受体本身无激酶活性,但...
Definition Tyrosine‐kinase‐associated receptors comprise of cell surface receptors for a large number of cytokines. Growth Factors Tyrosine KinasesDefinitionTyrosine‐kinase‐associated receptors comprise of cell surface receptors for a large number of cytokines.Growth Factors Tyrosine KinasesGrowth Factors...
Tyrosine kinase receptors are a type of receptor that consist of an external N-terminal segment and an internal C-terminal segment. When these receptors are activated, they stimulate the activity of the tyrosine kinase enzyme in the internal domain and cause the phosphorylation of specific molecules...
Again, calling out the unique properties of the ErbB family of RTKs – the kinase activity of these receptors is activated through a unique allosteric mechanism whereby the C-lobe of one kinase domain in the dimer pair (the so called ‘activator’ kinase) physically contacts the N-lobe of t...
Angiotensin II and other hypertrophic stimuli mediated by G protein-coupled receptors activate tyrosine kinase, mitogen-activated protein kinase, and 90-kD... Many hypertrophic stimuli such as angiotensin II (Ang II) activate phospholipases through G protein-coupled receptors in cardiac myocytes. ...
One of the key signaling components associated with RTKs is the phosphatidylinositol-3-kinase (PI3K) signaling transduction pathway. This pathway is also activated by cytokine receptors and G-protein–coupled receptors (GPCRs). Among the many functions of this pathway in hematopoietic cells, the IL...
Receptors, Cell SurfaceThe feline c-fms proto-oncogene product is a 170 kd glycoprotein with associated tyrosine kinase activity. This glycoprotein was ... CJ Sherr,CW Rettenmier,R Sacca,... - 《Cell》 被引量: 2975发表: 1985年 VEGF regulates haematopoietic stem cell survival by an internal...
Caveolin 1-Mediated Regulation of Receptor Tyrosine Kinase-Associated Phosphatidylinositol 3-Kinase Activity by Ceramide Previous studies have indicated that proapoptotic stresses downregulate the phosphatidylinositol 3-kinase [PI(3)K]/Akt survival pathway via the activation ... Wayne,Zundel,Lillian,... ...
Optical control over the activity of receptor tyrosine kinases (RTKs) provides an efficient way to reversibly and non-invasively map their functions. We combined catalytic domains of Trk (tropomyosin receptor kinase) family of RTKs, naturally activated b
While each microtubule-associated protein ha... G Lee,ST Newman,DL Gard,... - 《Journal of Cell Science》 被引量: 707发表: 1998年 The Role of Src in Solid Tumors The proto-oncogene c-Src (Src) encodes a nonreceptor tyrosine kinase whose expression and activity are correlated with ...