Tumor-derived exosome (TEX)cancer vaccineimmunotherapyDendritic cells (DCs)Identification of immunogenic tumor antigens that are efficiently processed and delivered by dendritic cells to prime the immune system and to induce an appropriate immune response is a research hotspot in the field of cancer ...
that BC-derived heparan sulfate (HS) could be carried by exosome particles, leading to upregulation of heparanase (HPSE) and HPSE2 expression of lymphocytes, which was highly relevant for cellular migration and tumor metastasis. Blomme et al. also showed that the cancer-overexpressed protein m...
肿瘤外泌体ELISA试剂盒又称Tumor-derived Exosome ELISA Kit,该产品是Abnova品牌提供的试剂盒,Abnova是驰名中外的单克隆抗体和蛋白生产商,截止到2017年,其现有抗体数量100000多种,蛋白近25000多种,并具有每月开发500种小鼠单克隆抗体和4536种兔源多克隆抗体的技术和实力。艾美捷科技作为中国区域代理商提供原装进口产品,并...
Contribution of MyD88 to the tumor exosome-mediated induction of myeloid derived suppressor cells. Am. J. Pathol. 176, 2490–2499 (2010). Article CAS PubMed PubMed Central Google Scholar Chemaly, R. F. et al. A multicenter study of pandemic influenza A (H1N1) infection in patients with...
This provocative study emphasizes that exosome-mediated signaling within the tumor microenvironment acts as a positive feedback loop that contributes to invasiveness and that interfering with this message delivery system may represent promising therapeutic approaches, not only for GIST, but for other types...
Tumor-derived exosomes carry proteins, lipids, and various nuclear acids that promote increased permeability of the vascular endothelial barrier, ultimately inducing CRC hematogenous metastasis and pre-metastatic niche formation [12]. Our preliminary clinical studies revealed elevated levels of exosome-...
Melanoma-Derived Exosomes Induce PD-1 Overexpression and Tumor Progression via Mesenchymal Stem Cell Oncogenic ReprogrammingPD-1exosomemelanoma/tumor progression... E Gyukity-Sebestyén,M Harmati,G Dobra,... - 《Frontiers in Immunology》 被引量: 0发表: 2019年 Neoplastic Reprogramming of Patient‐Deri...
Suppression of in- flammation by tumor-derived exosomes: a kind of natural liposome packaged with multifunctional proteins. J Liposome Res. 2012; 22: 346... Hong,Teng,Min,... - 《Journal of Liposome Research》 被引量: 18发表: 2012年 Emerging Concepts of Tumor Exosome–Mediated Cell-Cell ...
Exosome-derived HMGB1 activated B cells and promoted TIM-1+Breg cell expansion via the Toll like receptor (TLR) 2/4 and mitogen-activated protein kinase (MAPK) signaling pathways.Our results illuminate a novel mechanism of TIM-1+Breg cell-mediated immune escape in HCC and provide functional evi...
Exosomes from breast cancer cells can convert adipose tissue-derived mesenchymal stem cells into myofibroblast-like cells. Int J Oncol 2012; 40: 130–8. 27 Milane L, Singh A, Mattheolabakis G, Suresh M, Amiji MM. Exosome mediated communication within the tumor microenvironment. J Control ...