However, since the introduction of trastuzumab as a potent therapeutic approach in HER-2-positive BC, HER-2 expression is perceived as a favorable predictive rather than negative prognostic factor [4., 5., 6.]. Triple-negative breast cancer (TNBC) is characterized by a lack of expression of...
Triple negative breast cancer: Deciphering the biology and heterogeneity. Med. Univ. 2016, 18, 105-114. [CrossRef]G. Uscanga-Perales, S. Santuario-Facio, and R. Ortiz-Lo´pez, "Triple negative breast cancer: Deciphering the biology and heterogeneity," Medicina Universitaria, vol. 18, no....
Triple negative breast cancer (TNBC), which accounts for 15–20% of incident breast cancers, is the only breast cancer (BC) subtype that lacks targeted treatments. Using clinical assays, TNBC is human epidermal growth factor receptor 2 (HER2) negative and has <1% expression of estrogen receptor...
Other forms of breast cancer, he noted, have so-called targeted agents. Disease positive for the HER2 receptor, for instance, can be treated with the monoclonal antibody trastuzumab (Herceptin). But there are no such agents for triple-negative cancer, limiting treatment options, he said. About ...
2-Hydroxychalcone和xanthohumol禁止三倍消极乳腺癌细胞入侵。 [translate] aTriple-negative breast cancer: BRCAness and concordance of clinical features with BRCA1-mutation carriers. 三倍消极乳腺癌: 临床特点BRCAness和和谐用BRCA1变化载体。 [translate] ...
one.Therearemanytreatmentoptions ortumorsthattest“positive,”but eweroptions orthosethatdon’t.Whatistriplenegativebreastcancer?Triplenegativebreastcancer(TNBC)getsitsnamebecausethecellstestnegative orthreereceptors.So,TNBCis:•Estrogenreceptor-negative(ER-);•Progesteronereceptor-negative(PR-);and•HER2...
aCurrent strategy for triple-negative breast cancer: appropriate combination of surgery, radiation, and chemotherapy. 当前战略为三倍消极乳腺癌: 手术、辐射和化疗的适当的组合。[translate] aturn up the voice 出现声音[translate] aClinical outcome of triple negative breast cancer in BRCA1 mutation carrier...
- 《Breast Cancer Basic & Clinical Research》 被引量: 63发表: 2009年 Pharmacotherapy of triple-negative breast cancer. Triple-negative has many histological and genetic similarities with BRCA-1-associated , suggesting a common and the potential use of common chemotherapeutics ... C Arslan,O ...
Image-Guided Vacuum Core Biopsy May Identify CR in HER2+ Breast Cancer and TNBC Following Neoadjuvant Therapy Russ Conroy January 15th 2023 Patients with HER2-positive breast cancer and triple-negative breast cancer may not require breast surgery if a pathological complete response can be identified ...
Have what your doctor will call aBRCA mutation(a change in a gene), especially the gene BRCA1 Are inactive and have obesity after menopause Diagnosing Triple-Negative Breast Cancer There's no way to know which type of breast cancer you have until you’re tested by a doctor.Usually, triple...