Women with Triple-Negative Breast Cancer Very Likely to Carry BRCA1 GenePhoebe Starr
FOXP3 transcription factor: a candidate marker for susceptibility and prognosis in triple negative breast cancer[J]. Biomed Res Int, 2014, 2014: 341654. [15] Chen Y, Qi X, Bian C, et al. The association of FOXP3 gene polymorphisms with cancer susceptibility: a comprehensive systemic review...
- 《Jnci Journal of the National Cancer Institute》 被引量: 2发表: 2018年 Precision medicine in breast cancer (Review) TRIPLE-negative breast cancerBRCA genesGENETICS of breast cancerTECHNOLOGICAL innovationsHORMONE receptor positive breast cancerPrecision medicine in breast cancer ... P Papalexis,VE...
basal-like breast cancer gene expression profiling molecular heterogeneity targeted agents triple-negative breast cancer introduction Breast cancer (BC) is the most common female cancer. More than 1 million women worldwide are affected by this diagnosis and ∼400 000 patients die due to the disease...
From the BRCA dataset, we focused on a specific type of breast cancer, the Triple-Negative Breast Cancer (TNBC), which is the most heterogeneous group of breast cancers, presenting a significantly shorter survival following the first metastatic event when compared with those with non-basal-like/...
Immunotherapy has recently emerged as a treatment strategy which stimulates the human immune system to kill tumor cells. Tumor immunotherapy is based on immune editing, which enhances the antigenicity of tumor cells and increases the tumoricidal effect o
TripleNegativeBreastCancer Whogetstriplenegative breastcancer? About15-20percentoallbreastcancersintheU.S. areTNBC.Anyonecangetthistypeobreastcancer. But,researchshowsthatitoccursmoreotenin: •Youngerwomen •AricanAmericanwomen •WomenwhohaveBRCA1genemutations ...
Triple-negative breast cancer (TNBC), a subgroup that lacks expression of hormone receptors and HER2, overlaps with basal-like breast cancer (BLBC), a subgroup that expresses cytokeratins and other non-luminal (basal) genes Breast cancers occurring in patients with germline BRCA1 mutations are oft...
Triple-Negative Breast Cancer Some breast cancers -- between 10% and 20% -- are known as “triple negative” because they don’t have estrogen and progesterone receptors and don’t overexpress the HER2 protein. Many breast cancers associated with the gene BRCA1 are triple negative. They are ...
Zhao, MD; Si Yang, MD; Jingjing Hu, MD; Bajin We, MD; Ying Wu, PhD; Dai Zhang, MD; Huafeng Kang, MD; Zhijun Dai, PhD JAMA Network Open Original Investigation Constitutional BRCA1 Methylation and Risk of Incident Triple-Negative Breast Cancer and High-grade Serous Ovarian Cancer Per E...