Triple-negative breast cancer (TNBC) is characterized by aggressive behavior and poor prognosis. While > 50 % of patients with inherited BRCA1 mutations have TNBC, the prevalence of BRCA1 mutations in patients with TNBC remains unclear. Deciphering the relationship between BRCA1 and TNBC is ...
et al. The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups. Nature 486, 346–352 (2012). Article CAS PubMed Google Scholar Lehmann, B. D. et al. Identification of human triple-negative breast cancer subtypes and preclinical models for selection of ...
10.Peter A. Fasching, Sibylle Loibl, Chunling Hu, et al. BRCA1/2 Mutations and Bevacizumab in the neoadjuvant treatment of breast cancer: response and prognosis results in patients with triple- negative breast cancer f...
Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer. J Clin Oncol. 2015;33:304–11. Article CAS PubMed Google Scholar Momozawa Y, Iwasaki Y, Parsons MT, Kamatani Y, Takahashi A, Tamura...
突变单侧乳腺癌患者(39.5岁 vs . 45.2岁, p =0.004).31例异时性双侧乳腺癌患者中首发癌和对侧癌三阴性乳腺癌的比例分别为61.3%和67.7%,而在165例单侧乳腺癌患者中,三阴性乳腺癌(triple negative breast cancer, tnbc)比例为57....
Triple-negative breast cancer (TNBC) represents 15 to 20% of all types of breast cancer; however, it accounts for a large number of metastatic cases and deaths, and there is still no effective treatment. The deregulation of microRNAs (miRNAs) in breast cancer has been widely reported. We pr...
aIdentification of prognosis-relevant subgroups in patients with chemoresistant triple-negative breast cancer. 预测相关的小群的证明在病人有chemoresistant三倍消极乳腺癌。 [translate] ahe failed to lead the Decepticons to any more than a sad existence on an asteroid 他在小行星再比哀伤的存在没有带领...
BRCA1 RING Domain is required for Nuclear Import and Growth Inhibition of Triple Negative Breast Cancer Cells 来自 ResearchGate 喜欢 0 阅读量: 13 作者:Y Qin,J Xu,K Aysola,T Watkins,VN Rao 摘要: Mutation in the BRCA1 gene is associated with increased risk for hereditary breast and ovarian ...
aFolate Receptor α Associated With Triple-Negative Breast Cancer and Poor Prognosis. 叶酸感受器官α联合三倍消极乳腺癌和恶劣的预测。[translate] aBRCA1 promoter methylation is a marker of better response to anthracycline-based therapy in sporadic TNBC. BRCA1促进者甲基化是更好的反应标志对基于anthracycl...
Mutation Analysis of BRCA1, BRCA2, PALB2 and BRD7 in a Hospital-Based Series of German Patients with Triple-Negative Breast Cancer Triple-negative breast cancer (TNBC) is an aggressive form of breast carcinoma with a poor prognosis. Recent evidence suggests that some patients with TNBC... F...