RNA polymerase reads the unwound DNA strand and builds the mRNA molecule, using complementary base pairs. There is a brief time during this process when the newly formed RNA is bound to the unwound DNA. During this process, an adenine (A) in the DNA binds to an uracil (U) in the RNA...
Multi-level and lineage-specific interactomes of the Hox transcription factor Ubx contribute to its functional specificity Many transcription factors regulate gene expression in a lineage- and process-specific manner, despite being expressed in several cell types. Here, the authors show that the Hox...
Organisms determine the transcription rates of thousands of genes through a few modes of regulation that recur across the genome1. In bacteria, the relationship between the regulatory architecture of a gene and its expression is well understood for individual model gene circuits2,3. However, a broa...
innovative strategies for crop protection. Immune gene expression in eukaryotic cells is first regulated at the transcription level, a process affected by the coordination between multiple cis- and trans-acting factors. Previous studies have demonstrated that multiple TF families, including WRKY, MYB, N...
3.5The Central Dogma of Molecular Biology: RNA Transcription and Processing Sections of DNA calledgenesencode the information needed to create proteins. There are over 20,000 protein-encoding genes within the 46 chromosomes that constitute thehuman genome. There are three steps in the process of gen...
Chang-HuiShen, inDiagnostic Molecular Biology (Second Edition), 2023 The order of events in eukaryotic transcription initiation Eukaryotic transcription is a complex, multistep process involving binding of RNA polymerase to the DNA, initiation, elongation, and production of a pre-mRNA transcr...
Upon termination, the process of transcription is complete. By the time termination occurs, the prokaryotic transcript would already have been used to begin synthesis of numerous copies of the encoded protein because these processes can occur concurrently. The unification of transcription, translation, ...
The computational biology methods offer a practical and stable foundation on which additional wet-lab research could be carried out. Numerous abiotic stresses have been connected to HSF genes. In the study, we examined this important gene family in detail using the whole annotated rice genome ...
Transcription profiling can be applied to stable loss- and gain-of-function transcription factor mutants to identify the global expression changes that are associated with the mutant phenotype, thereby facilitating placement of the transcription factor in a developmental pathway or process. From: Plant ...
A transcription initiation site is the location on a DNA molecule where the process of transcription begins. It determines the structure of the 5'-UTR and can contain features that inhibit translation. AI generated definition based on: Mechanisms of Development, 2001 ...