Theoretical basis of admixture GWAS study designs. (a)Populations 1 and 2 are two parental populations in which there has been no gene flow historically. When these populations interbreed the subsequent F1 population includes heterozygotes. Over the course of 5 or 10 generations the chromosome of ...
Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets. Nat. Genet. 48, 481–487 (2016). Article CAS PubMed Google Scholar Chen, E. Y. et al. Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool. BMC Bioinformatics 14, 128 (...
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(highest black points) shows the most significant enrichment is for kidney samples, which are highly ranked for the top 1000 CpGs associated with eGFR.bFORGE2 analysis for eGFR SNPs from GWAS catalog: thexaxis indicates tissues/cell type samples used in the analysis; theyaxis shows FORGE2 ...