TNFalpha-stimulated gene-6 (TSG6) activates macrophage phenotype transition to prevent inflammatory lung injury. Proc Natl Acad Sci U S A. 2016;113(50):E8151-8.Mittal M, Tiruppathi C, Nepal S, et al. TNFalpha-stimula...
TSG-6 (TNF-stimulated gene 6; also TNFIP6) is a secreted, 35-39 kD group A member of the LINK-Module superfamily of proteins (1-4). Mouse TSG-6 is synthesized as a 275 amino acid (aa) precursor. It contains a 17 aa signal sequence and a 258 aa mature reg
TNF-alpha stimulated the release of GM-CSF, IL-6 and IL-8 and, combined with IL-1 alpha, cytokine production was enhanced synergistically. Finally, both LPS and IL-1 alpha up-regulated ICAM-1 and VCAM-1 gene expression. These findings implicate duodenal fibroblasts in the initiation and/or...
Implantation of DFAT cells decreased expression of interleukin (IL)-6 and IL-12β mRNAs and increased expression of TNF-stimulated gene (TSG)-6 mRNA in renal cortex from mAb 1-22-3-injected rats. The basal level of TSG-6 protein was significantly higher in DFAT cells than in fibroblasts...
TSG-6 (TNFAIP6, TNF-stimulated Gene 6 Protein, TSG6)| 基本信息 更多信息 中文名称: 中文同义词: 英文名称: TSG-6 (TNFAIP6, TNF-stimulated Gene 6 Protein, TSG6) 英文同义词: TSG-6 (TNFAIP6, TNF-stimulated Gene 6 Protein, TSG6) CAS号: 分子式: 分子量: 0 EINECS号: 信息错误...
The trophic secretome of MSCs includes soluble factors, such as transforming growth factor-β (TGF-β), IL-10, prostaglandin E2 (PGE2), indoleamine 2,3-dioxygenase (IDO), and tumor necrosis factor α (TNFα)-stimulated gene protein-6, which contribute to MSC-mediated immunosuppression3,4. ...
Increased proliferation of endothelial cells with overexpression of soluble TNF-α receptor I gene Vascular endothelial growth factor (VEGF) can overcome a potential anti-angiogenic effect of TNF-α by inhibiting endothelial apoptosis induced by this cyt... M Sakuma - 《Atherosclerosis》 被引量: 54...
Acetylation, a type of post-translational modification, is considered an important mechanism in the regula- tion of gene expression via activation of nuclear histone proteins; it regulates the functions of multiple cytoplas- mic proteins involved in cell survival, proliferation, and death, as well ...
展开 关键词: ACTIVATED PROTEIN-KINASE PROSTAGLANDIN D-2 GENERATION HUMAN PROSTATE-CANCER TUMOR-NECROSIS-FACTOR PROINFLAMMATORY CYTOKINES INFLAMMATORY RESPONSES GENE-EXPRESSION ALLERGIC-ASTHMA MURINE MODEL DOI: 10.4062/biomolther.2013.068 被引量: 61 年份: 2013 收藏...
It has recently been reported that c- myc is an inducible gene, regulated directly by growth signals which promote proliferation and expressed in a cell-cycle dependent manner 1 . Because various leukaemic cell lines express high levels... M Einat,D Resnitzky,A Kimchi - 《Nature》 被引量:...