TNFalpha GENE EXPRESSION AS A BIOMARKER OF SENSITIVITY TO ANTAGONISTS OF INHIBITOR OF APOPTOSIS PROTEINSTNF伪 gene expression can be used as a biomarker of a cell's sensitivity to antagonists of inhibitor of apoptosis proteins (IAPs). Methods of the invention are useful for screening patients to ...
Pires et al., "Long-term resistance training is associated with reduced circulating levels of IL-6, IFN-gamma and TNF-alpha in elderly women," Neuroimmunomodulation, vol. Effects of Resistance Training on Immunoinflammatory Response, TNF-Alpha Gene Expression, and Body Composition in Elderly Women...
此外,由 LTA基因编码的同样隶属于TNSF超家族的TNF-β蛋白,也称为淋巴毒素α(Lymphotoxin Alpha,LT-α),也能与TNFR1和TNFR2相结合。 图2. TNFR1与TNFR2介导的信号通路[3] 小结 作为一种细胞因子,TNF-α在免疫反应中发挥了重要作用,包括促进炎症反应、细胞增殖和分化、细胞凋亡和坏死等。此外,TNF-α的过表达...
As an alternative technology, we applied highly efficient gene-targeting with recombinant adeno-associated virus to precisely integrate a luciferase reporter gene into exon 1 of the HeLa cell tumor necrosis factor-alpha (TNF-α) gene. Drugs known to induce TNF-α expression were then used to ...
此外,由 LTA基因编码的同样隶属于TNSF超家族的TNF-β蛋白,也称为淋巴毒素α(Lymphotoxin Alpha,LT-α),也能与TNFR1和TNFR2相结合。 图2. TNFR1与TNFR2介导的信号通路[3] 小结 作为一种细胞因子,TNF-α在免疫反应中发挥了重要作用,包括促进炎症反应、细胞增殖和分化、细胞凋亡和坏死等。此外,TNF-α的过表达...
此外,由 LTA基因编码的同样隶属于TNSF超家族的TNF-β蛋白,也称为淋巴毒素α(Lymphotoxin Alpha,LT-α),也能与TNFR1和TNFR2相结合。 图2. TNFR1与TNFR2介导的信号通路[3] 小结 作为一种细胞因子,TNF-α在免疫反应中发挥了重要作用,包括促进炎症反应、细胞增殖和分化、细胞凋亡和坏死等。此外,TNF-α的过表达...
[37] Azuma Y, KatogiR. Tumor necrosis factor alpha induces differentiation of and bone resorption by osteoclasts[J]. J Biol Chem, 2000, 275(7): 4858-4864. DOI:10.1074/jbc.275.7.4858. [38] Sumiyoshi R, Koga T, T...
Brief hypoxia differentially regulates LPS-induced IL-1beta and TNF-alpha gene transcription in RAW 264.7 cells Episodes of tissue hypoxia and reoxygenation frequently occur during gram-negative bacteremia that progresses to septic shock. However, few studies have ev... MM Ndengele,CJ Bellone,AJ Le...
disfiguring inflammation, hyperpigmentation, scarring, and psychological impact.#The purpose of this study was to investigate the significance of two genetic variants in the promoter region of the tumor necrosis factor‐alpha (TNF‐α) gene and their association with insulin resistance (IR) in acne ...
TNF-alpha TNF, macrophage-derived TNF, monocyte-derived TNFA TNFSF2 TNLG1F tumor necrosis factor alpha tumor necrosis factor ligand 1F tumor necrosis factor ligand superfamily member 2 tumor necrosis factor-alpha 基因序列:NCBI_Gene:7124 蛋白序列:UniProtKB:P01375 ...