TNF-α gene knockout in triple negative breast cancer cell line induces apoptosis. Int J Mol Sci 2013;14:411-20.V. Pileczki, C. Braicu, C. D. Gherman, and I. Berindan- Neagoe, "TNF-α gene knockout in triple negative breast cancer cell line induces apoptosis," International Journal...
Knowledge of susceptibility genes of SDICH, a common complex disease, is largely lacking because of the study obstacles of the need ofa prioriknowledge of gene function, modest genetic effect, polygenic effect, and epistasis. The study herein shows that the common genetic variations ofTNF-αgene ...
AIM: To investigate the polymorphism of tumor necrosis factor-α (TNF-α) gene promoters in Chinese Han people, and to clarify whether such polymorphism was associated with the outcome of hepatitis B virus infection. METHODS: After the process of extracting genomic DNA from blood in 165 subjects...
In addition, it was shown that important determinants of prognosis of COPD such as FEV1, BMI, COPD exacerbation and hospitalization were not associated with TNF-α-308 gene polymorphism. 展开 关键词: Chronic obstructive pulmonary disease Genetics Polymorphism Tumor necrosis factor-α Doença pulmonar...
Current cell-based drug screening technologies utilize randomly integrated reporter genes to index transcriptional activity of an endogenous gene of interest. In this context, reporter expression is controlled by known genetic elements that may only partially capture gene regulation and by unknown features...
北京协和医院检验科窦亚玲教授等人在2022年1月发表于“Frontiers in Pharmacology”上的文章“Tumor Necrosis Factor Alpha -308G/A Gene Polymorphisms Combined with Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratio Predicts the Efficacy and Safety of Anti-TNF-α Therapy in Patients with Ankylosing Spon...
No allelic variant associations of the IL-1 and TNF gene polymorphisms in the susceptibility to duodenal ulcer disease Recent studies have reported the association of a pro-inflammatory profile of genetic polymorphisms in IL-1B , IL-1RN , TNF-A , and IL-10 genes with an inc... MA Garcia...
Role of TNF-alpha gene variation in idiopathic childhood ischemic stroke: a case-control study. P. ZOU (2009): Role of TNF-alpha gene variation in idiopathic childhood ischemic stroke: a case-control study, J Child Neurol; 24(1):25-9... Shi, K.-L.,B He,Wang, J.-J.,... - 《...
Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states.Nature medicine. NFATC3 promotes IRF7 transcriptional activity in plasmacy--toid dendritic cells.The Journal of experimental medicine. ...
has been shown to increase transcription of the gene in adipocytes. Aim of this study is to investigate the role of the G-308A TNF?? variant in obesity and to study the possible influence of this mutation on body fat distribution and on measures of obesity (including Fat Free Mass, Fat ...