At least one minor allele of the CARD15 gene was carried by 46% patients and only 21% control subjects (OR = 3.2, 95% CI 2.4–4.4). In a multiple logistic regression model, the strongest association with CD was found for the 1007fs variant (OR = 4.6, 95% CI 3.0–7.0), followed ...
Objective: Based on its function in immune response tumor necrosis factor-alpha (TNFa) has been regarded as a candidate gene for inflammatory diseases, including periodontal disease and Crohn's disease (CD). However, the results regarding the impact of genetic characteristics of TNFa on both diseas...
NOD2/CARD15 was described as the first susceptibility gene to Crohn's disease (CD). Polymorphisms in the TNFA gene and in the IL1 gene cluster, which are a... AC Ferreira,S Almeida,M Tavares,... - 《Inflammatory Bowel Diseases》 被引量: 137发表: 2005年 Association of NOD2/CARD15 ...
Novel heterozygous C243Y A20/TNFAIP3 gene mutation is responsible for chronic inflammation in autosomal-dominant Behet's disease Although Behçet's disease (BD) is a chronic inflammatory disorder of uncertain aetiology, the existence of familial BD with autosomal-dominant traits su......
TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma J Exp Med, 206 (5) (2009), pp. 981-989 CrossrefView in ScopusGoogle Scholar 10 MQ Du MALT lymphoma: many roads lead to nuclear factor-κb activation. Histopathology, 58 (1) (2011), ...