Tietze C,Blomeke B.Sensitization assays:monocyte-derived dendritic cells versus a monocytic cell line (THP-1).Journal of Toxicology and Environmental Health. 2008Tietze, C. and Blomeke, B. (2008). Sensitization assays: monocyte-derived dendritic cells versus a monocytic cell line (THP- 1). J...
TLR9 is mainly expressed in subsets of Dendritic Cells and in B cells of all mammals. In rodents, but not in humans, TLR9 is also expressed in monocytes and macrophages [3]. The structure of the receptor varies by 24% between human TLR9 (hTLR9) and mouse TLR9 (mTLR9) [3]. They rec...
TLR7 is mainly found in plasmacytoid dendritic cells (pDCs) and B cells, whereas TLR8 is highly expressed in monocytes, monocyte-derived DCs (mDCs), and macrophages [3]. TLR7 and TLR8 trafficking and signaling Upon viral infection, the chaperone protein UNC93B1 interacts with TLR7 and ...
THP-1 monocytes are described to differentiate into mature dendritic cells by transferring them to serum-free medium, and subsequently treating them with a mixture of IL-4, GM-CSF, TNF-α and ionomycin. These hematopoietic cell line-derived DCs are highly pure and monotypic, and display the mo...
MUTZ-3-derived dendritic cells as an in vitro alternative model to CD34+ progenitor-derived dendritic cells for testing of chemical sensitizers [J]. Toxicol Vitro, 2009, 23 (8): 1477-1481. [22] Beutler B, Cerami A. The biology of cachectin/TNF: A primary mediator of the host response ...
Dendritic cell-specific intercellular adhesion molecule-3 grabbing nonintegrin (DC-SIGN) is an important pattern recognition receptor on dendritic cells (DCs), and its expression shows significant cy...
Comparative analysis of integrin expression on monocyte-derived macrophages and monocyte-derived dendritic cells. Immunology 100, 364–369 (2000). Article CAS PubMed PubMed Central Google Scholar I, K.-Y. et al. Activation of adhesion GPCR EMR2/ADGRE2 induces macrophage differentiation and ...
Monocytes are circulatory precursor cells from myeloid origin that can develop into macrophages or dendritic cells upon migration from the blood stream to tissues. Both macrophages and dendritic cells are professional antigen-presenting cells. Monocytes
Karla A.Aguayo-Cerón, …,Claudia C.Calzada-Mendoza Comparability study of monocyte derived dendritic cells, primary monocytes, and THP1 cells for innate immune responses Journal of Immunological Methods, Volume 498, 2021, Article 113147 YiWen, …,ArunanKaliyaperumal...
TPL-2 negatively regulates interferon-beta production in macrophages and myeloid dendritic cells. J Exp Med 2009; 206: 1863–1871. Article CAS Google Scholar Pastore L, Tessitore A, Martinotti S, Toniato E, Alesse E, Bravi MC, Ferri C, Desideri G, Gulino A, Santucci A . Angiotensin II...