Monocytes are circulatory precursor cells from myeloid origin that can develop into macrophages or dendritic cells upon migration from the blood stream to tissues. Both macrophages and dendritic cells are professional antigen-presenting cells. Monocytes and their macrophage and dendritic-cell progeny serve...
CNP: C-type natriuretic peptide, peptide with anti-inflammatory, anti-proliferative, and anti-migration properties. b NPR: natriuretic peptide receptor. We have also performed a literature search to obtain data on a comparison of responses between THP-1 and human PBMC-derived macrophages. Reports ...
Meanwhile, this finding indicates that DHA can prevent Aβ-induced necroptosis of THP-1 cells via the RIPK1/RIPK3 signaling pathway. Our results also indicate that DHA treatment restored migration of THP-1 monocytes induced by Aβ25-35, and DHA treatment could be a promising new therapy for...
Tuberculosis (TB) is a zoonotic infectious disease caused by Mycobacterium tuberculosis (Mtb). Apoptosis and necrosis caused by the interaction between the host and the pathogen, as well as the host’s inflammatory response, play an important role in the
Trichinella spiralis is a foodborne zoonotic nematode, which causes trichinellosis. During the infection, parasite evades the host immune responses by dire
Cells were incubated for 48 h in growth medium without (control) or with puromycin (0.1–1 μg/ml). Cell survival was assessed by Trypan blue. All cells were dead in the presence of 0.6 μg/ml of puromycin, and this concentration of puromycin was used in the selection protocol. ...
2C). In contrast, the average migration did not differ (PE-EVs = 0.142 ± 0.003; HP-EVs = 0.139 ± 0.006 slope, P > 0.05; Fig. 2D). We also determined the effects of pregnancy-associated EVs on the adhesiveness of THP-1 cells by a real-time impedance-based method. ...
THP-1 cells were incubated with PMA for 24 h, followed by assay of adherence, morphological change, migration or IL-1β release. L-NG-Nitroarginine methyl ester (l-NAME, a nitric oxide synthase inhibitor) or BAPTA-AM (a calcium chelator) was added before PMA stimulation, and levels of ...
Thus, both nanobodies might result in impaired migration, although this is more likely for FASNb5, as we also observed reduced podosome translocation towards the cell sides (Fig. 6g). Thus, both nanobodies affect the adhesive, degrading and migratory phenotype due to podosome-loss. 4.4. ...
Monocytes are circulatory precursor cells from myeloid origin that can develop into macrophages or dendritic cells upon migration from the blood stream to tissues. Both macrophages and dendritic cells are professional antigen-presenting cells. Monocytes and their macrophage and dendritic-cell progeny serve...