UV phototriggered base proliferation reaction, which integrated the safety and strong penetrating ability of UV photopolymerization as well as Domino free radical photopolymerization based on phototriggered base proliferation reaction, is expected to expand the application of thiol-ene Michael addition ...
Thus, Michael addition might not be considered as stimuli induced system and excluded from this review. Moreover, apart from thiol-ene/yne systems, thiols also selectively react against several functional group like epoxides [495–499], oxazines [246,500–502] etc. and such reactions can be ...
The thiol-ene Michael-type addition (today sometimes named as “thiol-ene click coupling”), a nucleophilic addition of thiols (“Michael donor”) to activated olefins (electron poor/withdrawing olefins, “Michael Acceptor”), is a common and versatile synthetic strategy, which involves low toxic...
The Michael addition-like thiol–ene reaction is a useful tool that can be used to tag proteins with high selectivity for the solvent-exposed thiol groups of proteins. To obtain insight into the bioconjugation of proteins with this method, a kinetic analysis was performed. New vinyl-substituted ...
Thekey attribute of the thiol-Michael addition reaction that makesit a prized tool in materials science is its modular "click"nature, which allows for the implementation of this highly efficient,"green" reaction in applications that vary from smallmolecule synthesis to in situ polymer modifications ...
YU ZhiQiang,CUI MengMeng,YAN JunJie & YOU YeZi CAS Key Lab of Soft Matter Chemistry;Department of Polymer Science and Engineering,University of Science and Technology of China,Hefei 230026,China.One-pot synthesis of hyperbranched poly(amido amine) clicked with a sugar shell via Michael addition ...
thiol Michael addition to electron-deficient carbon–carbon double bonds. The reaction of thiols with enes, whether proceeding by a radical (termed thiol–ene reaction) or anionic chain (termed thiol Michael addition), carry many of the attributes of click reactions. These attributes include achievin...
N. A new photoclick reaction strategy: photo-induced catalysis of the thiol-Michael addition via a caged primary amine. Chem. Commun. 49, 4504-4506 (2013).A new photoclick reaction strategy:photo-induced catalysis of the thiol-Michael addition via a caged primary amine. Xi W,Krieger M,Klox...
Upon addition of tris (2-carboxyethyl) phosphine, the thiol-ene Michael addition reaction between GSH and AA was efficiently catalyzed, resulted in the quenched fluorescence triggered on. Under the optimum conditions, a linear detection range from 0.1 to 104μM was implemented for AA with a ...
Thiol–ene 'click' chemistries have been widely used in biomaterials applications, including drug delivery, tissue engineering, and controlled cell culture, owing to their rapid, cytocompatible, and often orthogonal reactivity. In particular, hydrogel-based biomaterials formed by photoinitiated thiol–ene ...