Then CCLMs were obtained via thiol-acrylate Michael addition reaction between the pendant acrylate group in the hydrophobic block and the crosslinker 1,6-hexanedithiol. DLS results showed that the CCLMs prepared from mPEG-b-poly(AC)25 were more stable than uncrosslinked micelles (UCLMs) upon ...
Main‐chain LCE networks were synthesized via a thiol‐acrylate Michael addition reaction. The robust nature of this reaction allowed for tailoring of the behavior of the LCEs by varying the concentration and functionality of the cross‐linker. The isotropic rubbery modulus, glass transition ...
Thekey attribute of the thiol-Michael addition reaction that makesit a prized tool in materials science is its modular "click"nature, which allows for the implementation of this highly efficient,"green" reaction in applications that vary from smallmolecule synthesis to in situ polymer modifications ...
The thiol-Michael addition was carried out by the addition of either mono acrylate or methylacrylate oligo(ethylene glycol) (1.1 equivalent) to a slightly basic (pH of 7.5, synthesized using 1 N NaOH) solution of l-cysteine. Reactions were quantitative, and high yields were obtained for all ...
Lastly, spatiotemporal control of both the thiol-ene reaction and thiol-Michael addition reaction were utilized to form a material with patterned functionalities and material properties, starting from a mixture of multifunctional thiols and an excess of multifunctional acrylates. This approach is based ...
Well-defined single-chain polymer nanoparticles via thiol-Michael additiondoi:10.1016/j.polymer.2017.05.040A synthetic strategy has been developed giving facile access to well-defined single-chain polymer nanoparticles (SCNPs) from styrene-, acrylate- and methacrylate-based polymers. Random copolymers (...
[reaction: see text] The Michael addition to alpha-substituted alpha,beta-unsaturated esters and amides using complex A containing a chiral odorless thiol ... K Nishide,Ohsugi, Shin-ichi,H Shiraki,... - 《Organic Letters》 被引量: 108发表: 2001年 The Reactivity and Oxidation Pathway of Cys...
Networks synthesized through thiol–acrylate photopolymerization or Michael-type addition step growth reactions contain esters with neighboring sulfide gro... AE Rydholm,KS Anseth,CN Bowman - 《Acta Biomaterialia》 被引量: 65发表: 2007年 Fluorinated networks through photopolymerisation processes: synthesis,...
Among the plethora of electron withdrawing activating groups that enable the Michael-type addition of sulfhydryl to olefins, acrylate esters, acrylonitrile, acrylamides, maleimides (MALs), alkyl methacrylates, cyanoacrylates, and vinyl sulfones are commonly used Michael acceptors because they are commerci...
The addition of thiol groups can also be used to add an additional reactive functionality to heparin that reacts with many existing polymer end groups (eg, acrylates, vinyl sulfones). The Prestwich lab developed a method for thiolation of glycosaminoglycans (GAGs), such as HA and heparin (Shu...