Lizcano JM,,Alessi DR.The insulin signaling pathway.. Current Biology . 2002Lizcano, J. M., and Alessi, D. R. (2002). The insulin signaling pathway. Curr. Biol. 12, 236-238. doi: 10.1016/S0960-9822(02)00777-7Lizcano JM,Alessi DR.The insulin signaling pathway. Current Biology . ...
The insulin signalling pathway 来自 Elsevier 喜欢 0 阅读量: 40 作者: Jose,M.,Lizcano,and,Dario,R.,Alessi 展开 DOI: 10.1016/S0960-9822(02)00777-7 被引量: 351 年份: 2002 收藏 引用 批量引用 报错 分享 全部来源 免费下载 求助全文 Elsevier Elsevier (全网免费下载) Semantic Scholar ...
Findings from non-clinical studies suggest that AJD101 stimulates insulin independent glucose uptake by directly activating the insulin signaling pathway. Ajinomoto, Sankyo in Joint Development, Manufacture and Marketing of AJD101, New Diabetes Drug More results ► Encyclopedia browser ? ▲ signal resh...
The insulin/insulin-like signaling pathway (IIS) has been shown to mediate life history trade-offs in mammalian model organisms, but the function of this pathway in wild and non-mammalian organisms is understudied. Populations of western terrestrial garter snakes (Thamnophis elegans) around Eagle Lak...
associated with the insulin signaling pathway, TNF signaling pathway, and AMPK signaling pathway. Molecular docking results and molecular dynamics simulation showed that most ginsenosides could stably bind to the core target, mainly hydrogen bonding and hydrophobic bond. This study suggests the management...
Comparative tranome profiling reveals that adenoma-like islet tumors are most similar to immature but differentiated insulin-producing β cells, whereas the invasive carcinomas are most similar to embryonic islet cell precursors. The progression toward poorly differentiated carcinomas involves a first step...
Endosomes help activate the hepatic insulin-evoked Akt signaling pathway, but the underlying regulatory mechanisms are unclear. Previous studies have suggested that the endosome-located protein WD repeat and FYVE domain–containing 2 (WDFY2) might be involved in metabolic disorders, such as diabetes....
Insulin is a protein hormone that controls the metabolism of sugar, fat and protein via signal transduction in cells, influencing growth and developmental processes such as reproduction and ageing. From nematodes to fruit flies, rodents and other animals
The current research was primarily focused on the P13K/AKT pathway, which is considered to be one of the key insulin signaling pathways. [66]. Moreover, the PI3K/AKT/GSK-3ß signaling pathway activation not only improves insulin sensitivity and glucose metabolism, but also exerts a beneficial...
Interestingly, genetic variations and nucleotid acid insertion in the 3′UTR of genes encoding glycoprotein PC-1 and protein tyrosine phosphate 1B (PTP1B), encoding inhibitors of the insulin signaling pathway have shown that these variations stabilize PC-1 and PTP1B and increase insulin resistance...