We previously reported that introduction of the wild-type p53 gene into human cancer cells with deleted p53 enhanced apoptosis induced by chemotherapy [Fujiwara et al. (1994) Cancer Res 54:2287]. This suggests that p53 status could be a potent determinant of the therapeutic efficacy of DNA-dama...
PJ Effert,A Neubauer,PJ Walther,ET Liu 摘要: P53 is a tumor suppressor gene that has been implicated in the molecular genetics of many human malignancies. Nucleotide alterations, most commonly single point mutations, have been shown not only to abrogate the p53 suppressor function but also to ...
Kaelin, W. 1999. The p53 gene family. Oncogene 18:7701-7705.Kaelin WGJ r. The p53 gene family[J ] . Oncogene , 1999 ,18 (53) :7 701 - 7 705.Kaelin W G Jr.The p53 gene family. Oncegene . 1999Kaelin W G Jr.The p53 gene family.Oncegene. 1999...
a工序流程图 Working procedure flow chart [translate] aThe P53 tumor suppressor gene product is a transcription factor involved in DNA repair. P53肿瘤遏抑器基因产品是在脱氧核糖核酸修理介入的副本因素。 [translate] 英语翻译 日语翻译 韩语翻译 德语翻译 法语翻译 俄语翻译 阿拉伯语翻译 西班牙语翻译 葡萄牙...
可能您是非常英俊的,可能您是非常逗人喜爱的,我可能爱以您。 [translate] aSo, I'm glad to meet you, 如此,我是高兴遇见您, [translate] aThe P53 tumor suppressor gene product is a transcription factor involved in DNA repair. P53肿瘤遏抑器基因产品是在脱氧核糖核酸修理介入的副本因素。 [translate] ...
摘要 Background and Purpose: P53 gene is a tumor suppressive gene and its product, P53 protein, is a protective factor aga... 被引量 1 收藏 全部来源 求助全文 Semantic Scholar 相似文献 引证文献 Thrombospondin-1 expression in bladder cancer: association with p53 alterations, tumor angiogenesis...
- 1992 - 123 - www.sciencedirect.comdoi:10.1016/0169-5002(92)90119-5NoneLung Cancer
ObjectiveEndometriosis is inherited as a complex trait, which means that multiple susceptibility genes interact with each other and the environment to produce the phenotype. Previous studies have implicated p53, a tumor suppressor gene, as a factor in the development of the disease. In a Japanese ...
For example, expression of the neoplastic phenotype is inhibited, rather than promoted, when rat cells are transfected with the murine wild-type p53 gene together with mutant p53 genes and/or other oncogenes 3,4 . Moreover, in human tumours, the short arm of chromosome 17 is often deleted ...
AIMS: To attempt to detect p53 gene mutations in the plasma of patients with large bowel carcinoma. METHODS: Plasma was collected from 20 control patients with no history of cancer and from 17 patients with large bowel carcinoma. Corresponding tumour and benign lymph node (control) samples for ...