protein‐protein interactionprotein stabilityp73KETThe p53 pathway provides a physiological system for integrating signals from diverse insults and eliciting adaptive cellular responses that include (but importantly are not restricted to) growth arrest and apoptosis. Defects in the pathway are prevale...
p53 protein, which accumulates intracellularly in over half of all human tumours, has also been reported to be present in the sera of patients with various malignancies, including lung cancer. Using a quantitative immunoassay, we measured p53 protein concentrations in 216 sera from 114 lung cancer...
p53 protein, which accumulates intracellularly in over half of all human tumours, has also been reported to be present in the sera of patients with various malignancies, including lung cancer. Using a quantitative immunoassay, we measured p53 protein concentrations in 216 sera from 114 lung cancer...
Although it is known that p53 protein accumulates as a result of genotoxic stress19 and p73 does not1,2, our results show that p73 is phosphorylated by a c-Abl-dependent mechanism in the DNA-damage response. The functional signi®cance of the c-Abl/p73 interaction is supported by our ...
抗P53抗体可从Aviva实验室获得2次 OAAI00414 |;抗P53抗体大小:1瓶| OAAI00469 |;抗P53抗体大小:1瓶| 目录号OAAI00469 供应商Aviva 价格 大小:1瓶。基因信息 identity1998 Gene TP53 Long Gene nametoma protein p53 Synonymsp53LFS1 Synonyms nameLi Fraumeni syndrome GenBank acessionAF307851 locs17p13.1 ...
;p53抗体; 是的尺寸:一瓶| 目录号OAAB16093 供应商aviva 价格 尺寸一瓶1。基因信息 identity1998 Gene TP53 Long Gene nametoma protein p53 Synonymsp53LFS1 Synonyms nameLi Fraumeni syndrome GenBank acessionAF307851 locs17p13.1 Discovery year1986-01-01 publimed identification639608734564882047879 Ref 产品...
Wild-type p53-induced phosphatase 1 is a prognostic marker and therapeutic target in bladder transitional cell carcinoma. Wang ZP,Chen SY,Tian Y. Oncol ... Z Wang,S Chen,Y Tian - 《Oncology Letters》 被引量: 0发表: 2017年 Expression of mitogen-activated protein kinase phosphatase-1 (MKP-...
P53 stability in tumour cells is not determined by mutation but is dependent on Mdm2 binding. Oncogene. 1997; 15 :1179–1189.Midgley, C. A. & Lane, D. P. (1997) Oncogene 15 , 1179-1189.Midgley CA, Lane DP. P53 protein stability in tumour cells is not determined by mutation but is...
Human Spot 14 protein is involved both in the regulation of malic enzyme promoter activity, and in the regulation of p53-dependent transactivation. It does not interact directly with p53, whereas it is able to directly interact with thyroid receptor and Zac1 (zinc finger protein which regulates ...
Currently, few immunohistochemical markers have been established to predict the prognosis of a canine MGT. However, p53 immunostaining has been variably reported to be prognostic for canine MGTs. Additionally, while p16CDK2NA protein (p16) immunostaining has been found to be prognostic for human ...