Methods and compositions for regulating the development and function of T helper (TH) cellsMethods and compositions for modulating T helper (Th) cell development and function using modulators of IL-21, e.g., human IL-21, activity or level.グラズビー, マイケル...
Objective To explore the subsets and function of T helper(Th) cells in bone marrow of the patients with immune-related pancytopenia(IRP).Methods By FACS,Th1 and Th2 cells in bone marrow were measured from normal control,IRP patients,aplastic anemia(AA) patients, myelodysplastic syndrome(MDS) pa...
aT cells can be classified into Th, CTL and Treg subtypes by their function.Depending on the capabilities to produce cytokines, Th can be divided to Th1,Th2, Th3, Th9, Th17, Th22 and Tfh subtypes t淋巴细胞可以被分类入Th、CTL和Treg子型由他们的作用。根据生产cytokines的有能力, Th可以被划...
Innate lymphoid cells: emerging insights in development, lineage relationships, and function. Annu. Rev. Immunol. 30, 647–675 (2012). Article CAS PubMed Google Scholar Zhu, J. T helper 2 (Th2) cell differentiation, type 2 innate lymphoid cell (ILC2) development and regulation of ...
Enhanced lymphatic function by blockade of IL-4 and IL-13. Thus far, we have shown that TH2 cells and their cytokines, IL-4 and IL-13, have an inhibitory effect on the formation of LVs and that this effect can be reversed with the neutralization of these cytokines. We next asked ...
2023年4月27日，来自美国国立卫生研究院的Daniella M. Schwartz研究团队在Nature Immunology上发表题为Dynamic chromatin accessibility licenses STAT5- and STAT6-dependent innate-like function of TH9 cells to promote allergic inflammation的文章，发现静息态的TH9细胞可以不依赖于T细胞受体的再刺激，而是通过依赖于...
1、Wang, Hongxing et al. T-Cell Immune Imbalance in Rheumatoid Arthritis Is Associated with Alterations in NK Cells and NK-Like T Cells Expressing CD38. Journal of innate immunity vol. 14,2 (2022): 148-166. 2、Ding Y, Wang Y, Zhang Y, et al. Alpha-linolenic acid improves nasal mucos...
1、Wang, Hongxing et al. T-Cell Immune Imbalance in Rheumatoid Arthritis Is Associated with Alterations in NK Cells and NK-Like T Cells Expressing CD38. Journal of innate immunity vol. 14,2 (2022): 148-166. 2、Ding Y, Wang Y, Zhang Y, et al. Alpha-linolenic acid improves nasal mucos...
Schaerli P., et al., (2000) Cxc Chemokine Receptor 5 Expression Defines Follicular Homing T Cells with B Cell Helper Function [J]. J Exp Med, 2000, 192(11): 1553-62.12. Wu HY., et al., (2008) Nasal anti-CD3 antibody ameliorates lupus by inducing an IL-10-secreting CD4+CD25-LAP...
顾名思义,辅助性T细胞(Th)为免疫系统的其他细胞提供辅助功能,特别是抗原提呈细胞(APC),如巨噬细胞、树突状细胞和B细胞,并对这些细胞的活化和成熟起到重要的作用。CD4+Th细胞有不同的亚群,包括Th1, Th2, Th9,Th17, Th22,Tfh和Treg细胞,每个亚群都由一组特定的细胞因子和转...