TGF- signaling in health and disease. Nat. Genet., 36: 790-792.Akhurst, R.J., 2004. TGF-b signaling in health and disease. Nat. Genet. 36, 790e792.Akhurst RJ. TGF-h signaling in health and disease. Nat Genet 2004;36:790-2....
TGFβ signaling in health and diseaseTGFβ signaling in health and diseaseAnimalsHumansMarfan SyndromeDNA-Binding ProteinsTrans-ActivatorsReceptors, Transforming Growth Factor betaSignal TransductionMutationPolymorphism, GeneticSmad Proteins1. Dietz, H. et al. Nat. Genet. 9, 228-229 (1995).2. Gilchrist...
Epidemiologic and clinical changes in the HIV epidemic over time have presented a challenge to public health surveillance to monitor behavioral and clinical factors that affect disease progression and HIV transmission. The Medical Monitoring Project (MMP) is a supplemental surveillance project designed to...
Blood vessel formation is a tightly regulated process that serves a critical role in both health and disease. Our lab has focused on the interactions between endothelial and smooth muscle cells that regulate proper blood vessel formation and function. In doing so, we identified miR-145 as a micr...
Effects of Different Combinations of Phytochemical-Rich Fruits and Vegetables on Chronic Disease Risk Markers and Gene Expression Changes: Insights from the MiBLEND Study, a Randomized TrialPrevious Article in Journal Isolation and Characterization of Antioxidant Peptides from Dairy Cow (Bos taurus) Place...
(This article belongs to the Special Issue Recent Advances in TGF-β Inhibitors for the Therapeutic Management of Cancer and Fibrosis)Download keyboard_arrow_down Browse Figures Versions Notes Abstract Idiopathic pulmonary fibrosis (IPF) is an irreversible and life-threatening lung disease of unknown...
RNS is caused by loss-of-function disease-causative variants of thegene that encodes a kinase that phosphorylates most of the secreted proteins found in the body fluids and extracellular matrix. The most common RNS clinical features are generalized osteosclerosis, facial dysmorphism, intracerebral ...
Walnut Phenolic Extract and Its Bioactive Compounds Suppress Colon Cancer Cell Growth by Regulating Colon Cancer Stemness Walnut has been known for its health benefits, including anti-cardiovascular disease and anti-oxidative properties. However, there is limited evidence eluc... J Lee,YS Kim,JH Le...
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, irreversible interstitial lung disease, with no effective cure. Polydatin is a resveratrol glucoside with strong antioxidant, anti-inflammatory and anti-apoptotic properties, which is used for treating health-related disorders such as cardiac...
DISEASEMICEEXPRESSIONtext>Due to the high morbidity and mortality rates, kidney diseases have been treated as a global health problem. However, the causes of their formation and development remains to be fully elucidated. High fat diet (HFD)-induced kidney injury has attracted increasing attention....