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TGF- signalingandthefibroticresponseANDREWLEASK1ANDDAVIDJ.ABRAHAMCentreforRheumatology,DepartmentofMedicine,RoyalFree&UniversityCollegeMed..
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TGF beta signaling pathway TheTransforming growth factor beta (TGFβ) signaling pathwayis involved in many cellular processes in both the adult organism and the developingembryoincludingcell growth,cell differentiation,apoptosis, cellular homeostasis and other cellular functions. In spite of the wide range...
The assembly of the Smad complex is critical for TGFb signaling. Yet, the mechanisms that inactivate or empower nuclear Smad complexes are less understood. By means of siRNA screen we identified FAM (USP9x), a deubiquitinase (DUB) acting as essential and evolutionarily conserved component in TGFb...
TGF-β signaling pathway inactivation and cell cycle deregulation in the development of gastric cancer: Role of the β-spectrin, ELF Katuri V, et al.TGF-beta signaling pathway inactivation and cell cycle deregulation in the development of gastric cancer: role of the beta-spectrin, ELF... SK ...
N-terminal pro-brain natriuretic peptide and other risk markers for the separate prediction of mortality and subsequent myocardial infarction in patients w... BACKGROUND: Biochemical markers are useful for prediction of cardiac events in patients with non-ST-segment-elevation acute coronary syndrome (...
TGFbetasignalingpathwayTheTransforminggrowthfactorbeta(TGFβ)signalingpathwayisinvolvedinmanycellularprocessesinboththeadultorganismandthedevelopingembryo..