TGFβ signaling in health and diseaseTGFβ signaling in health and diseaseAnimalsHumansMarfan SyndromeDNA-Binding ProteinsTrans-ActivatorsReceptors, Transforming Growth Factor betaSignal TransductionMutationPolymorphism, GeneticSmad Proteins1. Dietz, H. et al. Nat. Genet. 9, 228-229 (1995).2. Gilchrist...
TGF-b signaling in health and disease. Nat. Genet. 36, 790e792.Akhurst, R.J., 2004. TGF- signaling in health and disease. Nat. Genet., 36: 790-792.Akhurst RJ. TGF-h signaling in health and disease. Nat Genet 2004;36:790-2....
N-terminal pro-brain natriuretic peptide and other risk markers for the separate prediction of mortality and subsequent myocardial infarction in patients w... BACKGROUND: Biochemical markers are useful for prediction of cardiac events in patients with non-ST-segment-elevation acute coronary syndrome (...
ME Choi,Y Ding,SI Kim - 《Seminars in Nephrology》 被引量: 109发表: 2012年 TGF-β-activated kinase-1: New insights into the mechanism of TGF-β signaling and kidney disease TGF-beta-activated kinase-1: new insights into the mechanism of TGF-beta signaling and kidney disease. Kidney Res...
Immunohistochemical studies revealed that TGF-β1 and its specific receptors are present in Leydig cells in biopsies from normal tissue or patients with SCO or H with or without LCH. Smad proteins, which are involved in TGF-β1 signaling, are also detected in both their phosphorylated (activated...
- happens. Led by researchers at Baylor College of Medicine, the team of scientists found that the Transforming Growth Factor beta (TGF-beta) signaling pathway in uterine cells protects against the disease by suppressing the overgrowth and transformation into cancer cells of the endometrium, the ...
Inhibitor of TGF-beta signaling pathway partly reversed osteogenesis induced by suppressed CCNA1. Furthermore, suppressed CCNA1 relieved bone mass of OVX mice in vivo. Conclusion Downregulation of CCNA1 could activate TGF-beta signaling pathway and promote bone formation, thus playing a role in ...
In the current work we aimed to elucidate the role of TGFBR3 in the TGF-β signaling pathway of MFS patients. This was investigated by the quantification of mRNA expression of TGFBR3 and TGFB, as well as a panel of TGF-β signaling-associated target genes in primary dermal fibroblasts of ...
Harrison T, Samuel BU, Akompong T, Hamm H, Mohandas N, Lomasney JW, Haldar K: Erythrocyte G protein-coupled receptor signaling in malarial infection. Science. 2003, 301: 1734-1736. Article CAS PubMed Google Scholar Auburn S, Diakite M, Fry AE, Ghansah A, Campino S, Richardson A, ...
TGF-β/Smad signaling pathway in fatty liver disease: a case-control study Zargar, Ali, Fallahet al Mol Biol Rep(2024) 51 (1), 1031 Abstract: Fatty liver disease is a metabolic disorder that recently has been classified into two categories: metabolic dysfunction-associated fatty liver disease...