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2. Moustakas A, Pardali K, Gaal A, HeldinCH. Mechanisms of TGF-beta signaling in regulation of cell growth anddifferentiation. Immunol Lett. 2002 Jun 3; 82(1-2): 85-91. PubMed ID: 12008039 3. Roberts AB, Derynck R. Meetingreport: signaling schemes for TGF-beta. Sci STKE. 2001 De...
9. Varelas X, Wrana JL, et al. The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway. Dev Cell. 2010 Dec 14; 19(6):831-44. 10. Zhang YE. Non-Smad pathways in TGF-beta signaling. Cell Res. 2009; 19...
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HeldinCH. Mechanisms of TGF-beta signaling in regulation of cell growth anddifferentiation. Immunol Lett. 2002 Jun 3; 82(1-2): 85-91. PubMed ID: 12008039 3. Roberts AB, Derynck R. Meetingreport: signaling schemes for TGF-beta. Sci STKE. 2001 Dec 18; 2001(113):PE43. PubMed ID: ...
TGF-β1高生物活性:经ELISA,CELL BASE验证 活性(Bioactivity) :ELISA Immobilized Mouse / Rat TGFB1, Tag Free (Cat. No. TG1-M5218) at 0.2 μg/mL (100 μL/well) can bind Biotinylated Mouse TGF-beta RII, His,Avitag (Cat. No. TG2-M82H5) with a linear range of 1-20 ng/mL (QC te...
纤维化(Fibrosis)是一种累及多个器官、不可逆转的病理过程,它的形成是指胶原蛋白(collagen)、纤维粘连蛋白(fibronectin, FN)、α-平滑肌肌动蛋白(alpha-smooth muscle actin, α-SMA)等细胞外基质(extracellular matrix, ECM)过度堆积,成纤维细胞向肌成纤维细胞分化,实际上这是器官组织修复的一个重要阶段。但是当组织...
9. Varelas X, Wrana JL, et al. The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway. Dev Cell. 2010 Dec 14; 19(6):831-44. 10. Zhang YE. Non-Smad pathways in TGF-beta signaling. Cell Res. 2009; 19(1):128-139. ...
转化生长因子 (Transforming growth factor beta,TGF-β) 是一类多功能的细胞因子,可由多种组织细胞产生。TGF-β 信号通路是由众多成员的多功能细胞因子,与相应的受体、细胞内信号转导分子组成的通路,能影响疾病发生和发展,调节基因的转录,控制着细胞周期,影响细胞的增殖、分化、黏附、转移和凋亡。值得注意的是,TGF...