转化生长因子 (Transforming growth factor beta,TGF-β) 是一类多功能的细胞因子,可由多种组织细胞产生。TGF-β 信号通路是由众多成员的多功能细胞因子,与相应的受体、细胞内信号转导分子组成的通路,能影响疾病发生和发展,调节基因的转录,控制着细胞周期,影响细胞的增殖、分化、黏附、转移和凋亡。值得注意的是,TGF-...
13. A B Kulkarni, et al. Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death.Proc Natl Acad Sci U S A. 1993 Jan 15;90(2):770-4. 14. B B Cazac, et al. and Jürgen Roes. TGF-β receptor controls B cell responsiveness and...
13. A B Kulkarni, et al. Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death.Proc Natl Acad Sci U S A. 1993 Jan 15;90(2):770-4. 14. B B Cazac, et al. and ...
13. A B Kulkarni, et al. Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death.Proc Natl Acad Sci U S A. 1993 Jan 15;90(2):770-4. 14. B B Cazac, et al. and Jürgen Roes. TGF-β receptor controls B cell responsiveness and i...
transforming growth factor betasystemic sclerosisfibrosisfibroblastsA homogeneous population of bone marrow-derived TGF尾-responsive cells, a method for their selection from bone marrow, and a method for expressing a recombinant protein from the bone marrow-derived cells. The selection comprises the steps...
转化生长因子 (Transforming growth factor beta,TGF-β) 是一类多功能的细胞因子,可由多种组织细胞产生。TGF-β 信号通路是由众多成员的多功能细胞因子,与相应的受体、细胞内信号转导分子组成的通路,能影响疾病发生和发展,调节基因的转录,控制着细胞周期,影响细胞的增殖、分化、黏附、转移和凋亡。值得注意的是,TGF...
转化生长因子 (Transforming growth factor beta,TGF-β) 是一类多功能的细胞因子,可由多种组织细胞产生。TGF-β 信号通路是由众多成员的多功能细胞因子,与相应的受体、细胞内信号转导分子组成的通路,能影响疾病发生和发展,调节基因的转录,控制着细胞周期,影响细胞的增殖、分化、黏附、转移和凋亡。值得注意的是,TGF...
7. TGF-β signallingattenuates tumourresponse to PD-L1 checkpoint blockade by contributing to retention of T cells in the peritumouralstroma; 8. Selective inhibition of TGFβ1 activation overcomes primary resistance to checkpoint blockade therapy by altering...
转化生长因子 (Transforming growth factor beta,TGF-β) 是一类多功能的细胞因子,可由多种组织细胞产生。TGF-β 信号通路是由众多成员的多功能细胞因子,与相应的受体、细胞内信号转导分子组成的通路,能影响疾病发生和发展,调节基因的转录,控制着细胞周期,影响细胞的增殖、分化、黏附、转移和凋亡。值得注意的是,TGF...
TGF- signalingandthefibroticresponseANDREWLEASK1ANDDAVIDJ.ABRAHAMCentreforRheumatology,DepartmentofMedicine,RoyalFree&UniversityCollegeMed..