Telomere and telomerase in stem cells. Br J Cancer. 2007;96(7):1020-4. doi:10.1038/sj.bjc.6603671.E Hiyama,K Hiyama.Telomere and telomerase in stem cells.British Journal of Cancer. 2007Hiyama E and Hiyama K: Telomere and telomerase in stem cells. Br J Cancer 96: 1020-1024, 2007....
In somatic cells, the activity of telomerase decreases after birth leading to shortening of telomere with , which thereby triggers ... B Choudhary,AA Karande,SC Raghavan - 《Frontiers in Bioscience》 被引量: 32发表: 2012年 Research progress of telomere and telomerase in tumor stem cells The...
Define telomerase. telomerase synonyms, telomerase pronunciation, telomerase translation, English dictionary definition of telomerase. n. An enzyme that is found in the telomeres of chromosomes in germ cells, stem cells, and most cancer cells and that pr
Telomere and telomerase in stem cells. Br. J. Cancer 96, 1020–1024 (2007). Article CAS PubMed PubMed Central Google Scholar Armanios, M. et al. Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita. Proc. Natl. Acad. Sci. ...
intelomeres[1]. Telomerase is active in stem cells and most cancer cells, but inactive insomatic cells[2]. Mutations in telomerase holoenzyme components lead to diseases collectively calledtelomerebiology disorders, and telomerase upregulation appears essential for the immortalization of cancer cells [2...
3. Telomerase in stem cells 4. Background review of cancer stem cells 5. Review of telomerase in cancer stem cells 6. Evidence for short telomeres in cancer stem cells 7. Self-renewal in cancer stem cells versus bulk tumor cells 8. Do cancer initiating/stem cells have different DNA strands...
aAlternative CD44 splicing in intestinal stem cells and tumorigenesis 接合在小肠干细胞和tumorigenesis的选择CD44[translate] aLook at this Earth 100, and parched. 看这地球100和烘。[translate] aTRAPping telomerase within the intestinal stem cell niche 诱捕telomerase在小肠干细胞适当位置之内[translate]...
Telomerase expression is silenced in most adult somatic tissues with the exception of adult stem cell (SC) compartments, which have the property of having the longest telomeres within a given tissue. Adult SC compartments suffer from telomere shortening associated with organismal aging until telomeres ...
1.Analysis on Proteomic Profiling of Human Bone Marrow Mesenchymal Stem Cells Transduced with hTERT Gene;转人端粒酶基因骨髓间充质干细胞的蛋白表达谱分析 2.Expression of Survivin Bax and hTERT in Cutaneous Malignant Melanoma and the Relationship Between Them;皮肤恶性黑素瘤凋亡相关基因Survivin Bax表达及其...
L. The role of telomeres in stem cells and cancer. Cell 152, 390–393 (2013). PubMed Google Scholar Aubert, G. Telomere dynamics and aging. Prog. Mol. Biol. Transl Sci. 125, 89–111 (2014). CAS PubMed Google Scholar Amit, M. et al. Clonally derived human embryonic stem cell ...