gbm.exp <- get_count("TCGA-GBM") lgg.exp <- get_count("TCGA-LGG") dataPrep_GBM <- TCGAanalyze_Preprocessing( object = gbm.exp, cor.cut = 0.6, datatype = "raw_count" ) dataPrep_LGG <- TCGAanalyze_Preprocessing( object = lgg.exp, cor.cut = 0.6, datatype = "raw_count" ) # ...
1.打开TCGA网站，输入需要下载的肿瘤类型 2.点击WXS后面的数字51 3.点击左上角File 4.选择WXS，Masked...
LGGGBM的主要峰值(LG1和LG2)在TP53相关信号通路中显示出明显的富集,并且与COSMIC的TP53峰值(C7)重叠,这说明了TP53在LGGGBM肿瘤中的差异性参与,其中更类似于GBM的肿瘤比其他LGG亚型显示出更低频率的TP53改变。 区分COADREAD亚型的特征代表了涉及Wnt信号传导的通路(CR4,图6B),这部分与COSMIC的Wnt信号传导C4和C19峰值...
LGG Brain Lower Grade Glioma 脑低级别胶质瘤 LIHC Liver hepatocellular carcinoma 肝细胞肝癌 LUAD Lung adenocarcinoma 肺腺癌 LUSC Lung squamous cell carcinoma 肺鳞癌 MESO Mesothelioma 间皮瘤 OV Ovarian serous cystadenocarcinoma 卵巢浆液性囊腺癌 PAAD Pancreatic adenocarcinoma 胰腺癌 PCPG Pheochromocytoma and...
GBM glioblastoma multiforme 多形成性胶质细胞瘤 HNSC head & neck squamous cell carcinoma 头颈鳞状细胞癌 KICH kidney chromophobe 肾嫌色细胞癌 KIRC kidney clear cell carcinoma 肾透明细胞癌 KIRP kidney papillary cell carcinoma 肾乳头状细胞癌 LAML acute myeloid leukemia 急性髓细胞样白血病 ...
GBM Glioblastoma Multiforme 胶质母细胞瘤 READ Rectal Adenocarcinoma 直肠腺癌 LAML Acute Myeloid Leukemia 急性髓系白血病 TGCT Testicular Germ Cell Tumor 睾丸生殖细胞肿瘤 THYM Thymoma 胸腺瘤 MESO Malignant Mesothelioma 恶性间皮瘤 UVM Uveal Melanoma 葡萄膜黑色素瘤 ...
query.met <- GDCquery(project = c("TCGA-GBM","TCGA-LGG"), legacy = TRUE, data.category = "DNA methylation", platform = "Illumina Human Methylation 450")query <- GDCquery(project = "TCGA-ACC", data.category = "Copy number variation", legacy = TRUE, file.type = "hg19.seg", ...
GBMGlioblastoma multiforme多形成性胶质细胞瘤 GBMLGGGlioma胶质瘤 HNSCHead and Neck squamous cell carcinoma头颈鳞状细胞癌 KICHKidney Chromophobe肾嫌色细胞癌 KIPANPan-kidney cohort (KICH+KIRC+KIRP)混合肾癌 KIRCKidney renal clear cell carcinoma肾透明细胞癌 ...
2.1TCGA数据库中筛选胶质瘤不同分级GBM和LGG转录组数据 GBM转录组数据筛选 TCGA数据库中收录了GBM病例共有617例,本研究通过如下设定进一步筛选数据:本研究通过如下设定进一步筛选数据:(1)Primary size: Brain;(2)Project: TCGA-GBM;(3)Disease Type: Gliomas;(4)Vital status: dead,alive,下载转录组HTSeq-Counts...
GBM glioblastoma multiforme 多形成性胶质细胞瘤 HNSC head & neck squamous cell carcinoma 头颈鳞状细胞癌 KICH kidney chromophobe 肾嫌色细胞癌 KIRC kidney clear cell carcinoma 肾透明细胞癌 KIRP kidney papillary cell carcinoma 肾乳头状细胞癌 LAML acute myeloid leukemia 急性髓细胞样白血病 ...