T cell receptor alpha-chain and beta-chain junctional region homology in clonal CD3+, CD8+ T lymphocyte expansions in Felty’s syndrome. Arthritis Rheum 1997; 40: 615–623.Bowman SJ, Hall MA, Panayi GS, et al. T cell receptor alpha-chain and beta-chain junctional region homology in ...
T cell receptors The T cell receptor is somewhat simpler. It is a heterodimer in which each polypeptide chain is composed of two domains, one variable and one constant. There are four possible polypeptide chains, α, β, γ and δ. A receptor is made up of a pairing of either α with...
[9] Hoffman E S, Passoni L, Crompton T, et al. Productive T-cell receptor beta-chain gene rearrangement: coincident regulation of cell cycle and clonality during development in vivo[J]. Genes Dev, 1996, 10(8): 948-962. [10] ...
1. Analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4-8- alpha/beta T cells demonstrates preferential use of several V beta genes and an invariant TCR alpha chain 2. An Invariant T Cell Receptor α Chain Defines a Novel TAP-independent Major Histocompatibility C...
High-throughput pairing of T cell receptor alpha and beta sequences. Sci. Transl Med. 7, 301ra131 (2015). PubMed Google Scholar Glanville, J. et al. Identifying specificity groups in the T cell receptor repertoire. Nature 547, 94–98 (2017). CAS PubMed PubMed Central Google Scholar ...
The T Cell Receptor plays a key role in the immune system. The specificity of the receptor is governed by the binding site formed from the mature alpha and beta chains (shown here) or gamma and delta chains in gamma/delta T Cells. It is the ability of this receptor to bind a complex...
The T cell receptor beta chain (TCRB) repertoires of different CD4+T cell subsets (true naive, TN; central memory, CM; regulatory, Treg; and stem cell-like memory, Tscm) were examined using next generation sequencing technology in 14 recently diagnosed patients with type 1 diabetes (T1D) ...
T-cell receptor delta-chain can substitute for alpha to form a beta delta heterodimer . Nature (1989) 340 :562–5.10.1038/340562a0 [ Cross Ref ]Hochstenbach F., and Brenner M.B. 1989. T-cell receptor δ-chain can substitute for α to form a βδ heterodimer . Nature. 340 :562...
Protein Experimental Models Kits Other Keywords Epitope Single-cell analysis T-cell receptor repertoire Complementarity-determining region 3 TCR alpha TCR beta TCR diversity Unbiased repertoire Paired analysis Clonotype * Reagents occurring with supplier names are extracted and shared by CiteAb.Related...
and Palacios,HV Boehmer 展开 摘要: Transfected T cell receptor (TCR) beta chain genes are expressed as homodimers on the surface of immature (Sci/ET27F) but not on mature (58 alpha-beta-) T cell lines which lack TCR alpha, gamma and delta chains. The homodimer on Sci/ET27F cells ...