[5] Luo W, Ma L, Wen Q, Wang N, Zhou MQ, Wang XN. Analysis of the interindividual conservation of T cell receptor alpha- and beta-chain variable regions gene in the peripheral blood of patients with systemic lupus erythematosus. Clin Exp Immunol. 2008 Dec;154(3):316-24. doi: 10.1111...
The genetically modified mammal is useful in studying immunological tolerance, in particular in the mechanisms of tolerance to and the rejection of tissue grafts, and in pregnancy. The animals are also useful for testing agents for biological activity in promoting or reducing immunological tolerance....
TCR clustering analysis was performed using GIANA64with default settings or by calculating the minimal Levenshtein edit distance between the alpha and beta chain CDR3s. A minimal edit distance threshold of 2 or less between any pair of TCRs was used to predict recognition of the same antigen. ...
Paired analysis of TCR alpha and TCR beta chains at the single-cell level in mice Paired analysis of TCRα and TCRβ chains at the single-cell level in mice. J Clin Invest. 2011; 121 :288–295. doi: 10.1172/JCI44752. [ Cross Ref ]↵ Dash P. , McClaren J. L. , Oguin T. ...
Learn about our SMARTer approach to single T-cell sequencing that obtains alpha-beta pairing information.
1 Cell engineering diagram and extended characterization of 19-HIT80BB cells. a, Diagram illustrating genetic T cell engineering strategy of 19-HIT and 19-HIT80BB cells. The alpha and beta chains of HIT directed against CD19 were targeted into the TRAC locus as previously described37. 80BB ...
Paired analysis of TCRalpha and TCRbeta chains at the single-cell level in mice. Characterizing the TCRalpha and TCRbeta chains expressed by T cells responding to a given pathogen or underlying autoimmunity helps in the development of vaccines and immunotherapies, respectively. However, our understan...
Ceredig, and A.G. Rolink. 2008. TCR-beta chains derived from peripheral gammadelta T cells can take part in alphabeta T-cell development. Eur. J. Immunol. 38:3520- 3529. http://dx.doi.org/10.1002/eji.200838668Bosco, N (2008) TCR-beta chains derived from peripheral gammadelta T ...
Erratum to: analysis of the TCR alpha and beta chain CDR3 spectratypes in the peripheral blood of patients with Systemic Lupus Erythematosus Wang J-F, Wang X-N: Analysis of the TCR alpha and beta chain CDR3 spectratypes in the peripheral blood of patients with Systemic Lupus Erythematosus.....
[5] Luo W, Ma L, Wen Q, Wang N, Zhou MQ, Wang XN. Analysis of the interindividual conservation of T cell receptor alpha- and beta-chain variable regions gene in the peripheral blood of patients with systemic lupus erythematosus. Clin Exp Immunol. 2008 Dec;154(3):316-24. doi: 10.1111...