C. (2014) Molecular architecture of the alphabeta T cell receptor-CD3 complex.Proc Natl Acad Sci U S A. 111, 17576-17581Birnbaum ME, Berry R, Hsiao YS, Chen Z, Shingu-Vazquez MA, Yu X, et al. Molecular architecture of the αβ T cell receptor-CD3 complex. Proc Natl Acad Sci ...
The IMS has also an important role in the assembly of the ETC complexes. The inner-membrane is considered the most protein-enriched membrane of the cell, with up to 42 subunits per complex, including some soluble subunits facing the IMS. Several mutations in the various subunits of these comp...
Quantifiable markers of this phenotype include stimulation of phosphoinositide hydrolysis, transcriptional induction of atrial natriuretic factor (ANF) gene expression, and an increase in myocardial cell size. The aim of the present work was to determine which alpha 1-adrenergic receptor subtype mediates ...
To study the processes of thymic development, we have established transgenic mice expressing and alpha/beta T cell antigen receptor (TCR) specific for cyto... Vasquez,N. J - 《Journal of Experimental Medicine》 被引量: 377发表: 1992年 Growth of epithelial cells in the thymic medulla is under...
Description: This WT31 monoclonal antibody recognizes the human alpha beta T cell receptor (TCR) complexed with the CD3 epsilon chain. Composed of a 44-kDa alpha and a 37-kDa beta chain, TCR specificity is typically determined by V alpha, J alpha, V beta, D beta, and J beta gene...
The possible existence and distribution patterns of alpha/beta- and gamma/delta-TCR+ cells, which are important constituents of immune surveillance and act via the CD3+ cell complex have not yet been elucidated in the healthy and inflamed conjunctiva.Paraffin-embedded conjunctival specimens included 18...
The TCR/CD3 complex recognizes and binds to major histocompatibility complex-bound antigen presented by antigen presenting cells such as B cells, dendritic cells, and macrophages. These events lead to T cell activation, resulting in cellular signaling and cytokine production. The WT31 monoclonal ...
the t cell antigen receptor (tcr) consists of a ligand-specific alpha/beta heterodimer non-covalently associated with five invariant chains including the cd3 gamma/delta/eta and zeta subunits, all of which are required for efficient surface expression. t cell activation through the tcr induces...
Alpha TC1 (αTC1) and Beta-TC-6 (βTC6) mouse islet cell lines are cellular models of islet (dys)function and type 2 diabetes (T2D). However, genomic characteristics of these cells, and their similarities to primary islet alpha and beta cells, are undefi
Description: The B20.1 monoclonal antibody reacts with mouse T-cell receptor (TCR) V alpha 2 chains. This antibody recognizes the majority of the TCR V alpha 2 subfamily in mice carrying the a, b and c haplotypes. The antibody also reacts with the products of T cell receptor, V delta ...