Hwang HY,Kim TG,Kim TY.Analysis of T cell receptor alpha-chain variable region(Valpha) usage and CDR3alpha of T cells infiltrated into lesions of psoriasis patients.. Molecular Immunology . 2006Analysis of T cell receptor alpha-chain variable region(Valpha) usage and CDR3alpha of T cells ...
T CELL RECEPTORS The T cell receptor (TCR) is a T cell surface structure that is comprised of a disulfide-linked heterodimer of highly variable α and β chains expressed at the cell membrane as a complex with the invariant CD3 chains. Most T cells that bear this type of receptor are ter...
in addition to T cells, engrafted in the second mouse cohort, we additionally assessed in vivo CAR T cell killing activity. Variable levels of CD19+B cells were observed
参考资料: Chen, J., Zhao, B., Lin, S., Sun, H., Mao, X., Wang, M., ...Xiong, Y. (2024). TEPCAM: Prediction of T-cell receptor–epitope binding specificity via interpretable deep learning. Protein Sci, 33(1), e4841. doi: 10.1002/pro.4841 Code: https://github.com/Chenjw...
Use of a variable α region to create a functional T-cell receptor δ chain. Proc Natl Acad Sci USA 1988;85:5634-5638.Guglielmi P,Davi F,d’Auriol L,et al.Use of a variable alpha region to create a functional T-cell receptor delta chain. Proceedings of the National Academy of ...
Interaction of the T cell receptor (TCR) with an MHC-antigenic peptide complex results in changes at the molecular and cellular levels in T cells. The outside environmental cues are translated into various signal transduction pathways within the cell, which mediate the activation of various genes ...
Studies in transgenic and inbred strains of have shown that the critical molecular interactions controlling positive selection involve major histocompatibility complex (MHC), T-cell receptor (), and or CD8 coreceptor molecules. Correlations have been established between MHC gene products and the percentag...
Adoptive cell therapy using patient-derived chimeric receptor antigen (CAR) T cells redirected against tumor cells has shown remarkable success in treating hematologic cancers. However, wider accessibility of cellular therapies for all patients is needed
英文名称:Recombinant Interferon Inducible T-Cell Alpha Chemoattractant (ITaC) 保质期:避免反复冻融。2-8°C不超过一个月,-80°C不超过12个月。 保存条件:2-8°C不超过一个月,-80°C不超过12个月 干扰素诱导T-细胞α亚族趋化剂(ITαC)重组蛋白的产生是应用了重组DNA或重组RNA的技术从而获得的蛋白质。
TCR: T-cell receptor TNF: Tumour necrosis factor UMI: Unique molecular identifier V: Variable References Presti E Lo, Dieli F, Meraviglia S. Tumor-Infiltrating γδ T Lymphocytes: Pathogenic Role, Clinical Significance, and Differential Programing in the Tumor Microenvironment. Front Immunol. ...