databasesepitopesfood allergiesfoodshuman diseasesIgEThis chapter describes how the Structural Database of Allergenic Proteins (SDAP) can be used to identify allergens and define structurally related allergenic proteins from different food sources. It also contains a list of websites that contain ...
1.5.4Databases for structural classification of proteins Murzin et al. (1995)constructed theSCOPdatabase, which provides a detailed and comprehensive description of the structural and evolutionary relationships of the proteins of known structures. For each protein, the classification has...
3.1Online databases of structural protein–protein interactions 3.1.1PSIMAP/PSIBASE The first protein interaction family map was created byPark et al. (2001). Individualprotein domaininteractions where classified by domain assignments into family–family interactions using SCOP. Sequential interact...
Over the years, a number of protein repeat families (PRFs) have been identified and collected in various protein pattern databases based on different pattern identification approaches such as HMM profiles in Pfam, regular expressions in PROSITE, etc., which have been integrated in InterPro and Uni...
Protein Data Bank (PDB): Database of Three-Dimensional Structural Information of Biological Macromolecules The Protein Data Bank (PDB) at Brookhaven National Laboratory, is a database containing experimentally determined three-dimensional structures of proteins,... JL Sussman,D Lin,J Jiang,... - 《...
Structural information on the interactions of proteins with other molecules is plentiful, and for some proteins and protein families, there may be 100s of available structures. It can be very difficult for a scientist who is not trained in structural bio
Recent interest in repeat proteins has arisen due to stable structural folds, high evolutionary conservation and repertoire of functions provided by these proteins. However, repeat proteins are poorly characterized because of high sequence variation between repeating units and structure‐based identification ...
Detailed information about protein interactions is critical for our understanding of the principles governing protein recognition mechanisms. The structures of many proteins have been experimentally determined in complex with different ligands bound either in the same or different binding regions. Thus, the...
32 In addition, allergen sequences from SDAP can be directly searched against protein sequences in the NR and PDB databases at the NCBI using a BLAST search33 implemented in SDAP. Peptide search Allergenic proteins are known to be cross-reactive if they have high sequence or structural ...
摘要: The PDB has created systems for the processing, exchange, query, and distribution of data that will enable many aspects of high throughput structural genomics.关键词: Proteins Proteome Protein Conformation Genomics Automatic Data Processing Internet Software Information Storage and Retrieval ...