protein structure databasesstructural genomicsSwiss‐modelMODBASEprotein structureprotein structure predictionprotein structure databasesstructural genomicsThree-dimensional structures of proteins are the key to their molecular function. Traditionally protein structures are determined by experiment. The large set of ...
DPFunc, a deep-learning-based tool, uses protein domain information to accurately predict protein functions and detect corresponding regions in protein structures. DPFunc serves as an effective tool for large-scale protein function prediction.
Protein Structure Prediction: Inroads to Biology due to new methods to extract the growing amount of information in sequence and structure databases and improved computational descriptions of protein ... D Petrey,B Honig - 《Molecular Cell》 被引量: 354发表: 2005年 MULTICOM: a multi-level combina...
To begin with, we need to do sequence alignment to find similar sequence as the target sequence in bio-databases.第二,进一步确认,在数据库中,是否存在,与目标序列相类似的已知序列的三维结构信息,如果有,可以利用已知序列的蛋白质三维结构信息,进行同源比较建模,从而获得目标序列的三维结构预测。we need to...
Computer analysis and structure prediction of nucleic acids and proteins. We have developed an integrated computer system for analysis of nucleic acid and protein sequences, which consists of sequence and structure databases, a r... K Minoru,K Petr,G Peter,... - 《Nucleic Acids Research》 被...
Methods for predicting and designing protein structures have made tremendous progress over the past decade. Increases in computing power and the rapid growth of protein sequence and structure databases have driven the development of new data-intensive and computationally demanding structure prediction methods...
Table 1.List of databases and servers for protein structures, structure prediction, stability and interactions Name of the database/web serverURL Structure and classification PDBhttp://www.rcsb.org/pdb/home/home.do SCOPhttp://scop.mrc-lmb.cam.ac.uk/scop/ ...
Methods that require the structure of both proteins in a complex to make a prediction are called partner-specific, and methods that can make interface predictions on individual unbound proteins are referred to as partner-independent. Some template-free methods, like ISPRED4 [24], are partner-inde...
0.3 Databases A list of suggested protein databases, more lists at CNCB. 0.3.1 Sequence Database UniProt DisProt MobiDB Peptipedia 0.3.2 Structure Database DatabaseDescription PDB The Protein Data Bank (PDB) is a database of 3D structural data of large biological molecules, such as proteins ...
Biomolecular Interaction Network Database (BIND) [7], Database of Interacting Proteins (DIP) [8], and the Molecular Interaction database (MINT) [9] are mainly used databases by researchers. However, there still exist some drawbacks to traditional high-throughput methods, such as being costly ...